36例朗格罕氏细胞组织细胞增生症的放射性核素骨显像特征

36例朗格罕氏细胞组织细胞增生症的放射性核素骨显像特征 36例朗格罕氏细胞组织细胞增生症的放射 性核素骨显像特征 !!!!?I?j!!????!!??US????!??!g??gfE!!?h!!??!?h!!!!!1 36???A?M???S???????????????t?????k?3?b?]?i???k?????? ?x???C?l???C?D???? (???c?b???X???!???F???]?F???????c????250021) UP????UE?????h?????A?M???S???????????????t??(LCH)???k?3?b?]?i???k??????Ug?????h?????b?(????36??LCH ???6???????k???????4???V14?????6??????SPECT???>?k??Ug?????h36??LCH???6???????k???x?b30???4?x?b?? 83?43?6Ug???V?????????614???4?h???????616??Ug?????x?b?614???4???????????????]???W?4???V4???????????Z SPECT?????>?k???????e?)???x?b?67???4?F?????????4?????4?e?????????x?b?66???4???W?????????s?j????U!?????? ?????4?F???W?????????e?????x?b?62???4????l??Ug????U!?)?????????????WLCH???]?W????????Ug?????hLCH?m?k?3 ?b?]?i???????k???V?0???????????????4SPECT?????>?k????????LCH???????????x?b???4???6?????5???m?mLCH ???????V???0???b???9??Ug UP???K??UE???????????t???e?A?M???S?????e???????k???eSPECT?????>?k?? ?V???(?????hR681?eR815???K?2???!?hA?????R???h1006i7901I(2010)12i71868i704 Thecharacteristicfindingsofradionuclideboneimagingin36patientswithlangerhanscellhistiocytosis SHENchao?4LVKuan?4WUZhi-xing NuclearDepartmentofShandongProvincialHospital?4AffiliatedtoShandongUniversity?4Jinan??Shandong250021?? P?4R?4China [Abstract]Objective?hiIFoexplorethecharacteristicfindingsofradionuclideboneimaginginpatientswithLCH?4Methods?h Toretrospectivelyanalyzethefindingsolwholebodyboneimagingin36patientswithLCH?4amongwhichSIiIECTskull tomographicimagingwasperformedrespectivelyin14cases?4Results?h30of36cases(83?43?6)hadthepositivefindingsin theirwholebodybonescans?4with14caseshavingsolitarybonelesionUgl6caseshavingmultiplebonelesion?414caseshad skullinvolvementwhichwasmostlyseenintheparietalboneandthetemporalbone?4with4temporalboneIesionswerede?? tectedbyskullSPECT?h7caseshadvertebraecolumninvolvementwhichmainlylledinthethoracicvertebraandlumbar vertebra?e6caseshadlongbonelesionwiththefemur?4humerus?4andtibiamostlyinvolved?4andthelesionsmainlyIiedin thediaphysis?eTheribandiliuminvolvementwererespectively2casesandlcase?4Skull?4vertebraecolumnandlongbone werethecommonsitesofboneinvolvementofLCH?4Conclusion?hSomecharacteristicfindingsweredetectedbywholebody boncscaninpatientswithLCH?4andSPECTcouldraisethepositiverateofskeletalinvolvementdetectionofLCH?4Thetl- nitedapplicationofthebothcouldplayagreatroleinthediagnosisandtherapyofLCH?4 [Keywords]Histiocytosis?4Langerhanscell?eWholebodybonescan?eBoneSPECT ?A?M???S???????????????t??(Langerhans cellhistiocytosis?CLCH)?W?????????????????t?j ??????????????Ug?O???D?????????(?j3???????h?? ?????b??????U!?????????????5?????????????5 ??Ll??Ug?N?7???????b?(????36??LCH???k?3?b ?]?i???k?????????C?F????LCH?m?k?3?b?]?i?? ?k???V?????????????C?????????LUg 1?????4???? ???6?????h?x??(1976??)?4?[?4???c?!?????????4???h?????c?b?? ?F?????4?F???F?5?C?F???????]?F?????????????? 1868 1?41???N?X?? ?J???????(????(?F??+????????)?????j IUgCH???636???C???V?[26???C??lo???C????1??40 ???C????9??Ug?D???????j????U!?+??????U!?+???? ????????U!?????????k???????????b??Ug???V???? ???b??????26???C?????????????5??6???C?????? ???5??4??Ug?D?????L????1?w?5Ug????3??Ug?? ???????6???+?????W????(?????????????6)?????? ?R???R?+???k??(?h???????????6)Ug 1?42?k???? ???m????GE?????t????InfiniaHawkeye4?? 2010???N20???N12?tJMedImagingV01?420No?4122010 ???DSPECT???C???????????(???????????v256?? 1024?C????140KeV?C????20?6?C?????t???j 12mins?SmUg???3iaf?Tci7MDP??3h?4???k?3?b?]?i ???????k???C?????????0??????????????SPECT ?????>?k???C???v64??64?C?R?????+?????!?k???C?? ?v256??256?C????U!???????k???????C?)Ug?k?3?b ????99mTci7MDP(???-??????????)?Z???????? ?????C???i?F???V???????C?k?3?R??????>95?6Ug ?P???m???j20??30mCi(740??1110MBq)?C????25 mCi(925MBq)Ug???B?????3?>???0?????S[(?? ??+1)?S(????+7)]???P???>??(925MBq)?????C ???3?????B?????????0?h??Ug???3???????4?Z???6 ?h???D?C?k?????????????C?????H?????5?????????B ?k???????????????>(10?6?D?5?W??El?H?R?????? ????5mg?Skg????)Ug???014?????6?m1?w?5??3 ???????????????L?V??2---4?s???k???4???d?s?k?? ???????????j3??6?w?5Ug 1?43?????(???4?d?? ?????????j???1?????C???W?????????k?3?b?? ?????g?]???????????t?(?b?X???????6?R???????? ?j???j???j???j?x?bUg?????Z?d?H???)?F?5???C?d ??Ug 2???? 36??LCH???6???????k???x?b?630??(?x ?b???j83?43?6)?C???????k???D?b?66??(?D?b?? 16?47?6)Ug6???D?b???6?????5X???????R?? SPECT?????>?k?????R????????Ug30?????k???x ?b?6?C???????g?]?k?3?b?(?1?614??(46?47?6)?C?? ???j???(?????k?3?b?????R?j???j?Ric?????5?[ia?k ?3?b?????jUg???R?????L???????????????jic???f ??ia?k?3?b?g?]????Ug14???????x?b?6?C????7???C ????4???C?M?J2???C?L????l???C???V4???????? ?????????k???????????k?3?b?????C?k?3?b?(?1?d ???H?????C????SPECT?????>?k???4??????????lj ?????k?3?b?g?]????Ug?)?????k?3?b?g?]?(?1?67 ??(23?43?6)?C???V???44???C???43???C?????3?g?C?? ???G???4???????????????j????Ug?????k?3?b?g?] ?(?1?66??(20?6)?C???V????3???C????2???C???? 1???C?????j????????ic???f??ia?g?]?k?3?b?????? ?R?o?y?b?k?3?b?g?]?????jUg?????k?3?b?g?]?(?1 ?62??(6?47?6)?C???????????C?????jic??????ia?g?] ?k?3?b?????jUg?????k?3?b?g?]?(?1?6l?? 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UE869 g2010???N20???N12??!??!dI??!g?lg!!!?h!!?8!?h!!!!!! ?515???[???????????????????????????V?)?????????g?]?k?3?b?????C?4?????(?????j LCH??2?????6???D??????4?w?5?4???? ???0?g?]?k?3?b?????????4?k??????39???[?????????????????????????????k?3?b?X?? ?????C??ti?h?e6???4???(???54???>?k?? ??iI?h?k?j?????????g?]?k?3?b?????4???4???D???????jLCH ??????Ug ???R?C?Z???????j?????b?????C???????????k?? ?????????????4???X???????????????m?H???C?H?8 ?????????d???W???????????????C???????5?????? 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