前颞叶切除脑功功能缺失的研究计划任务书

前颞叶切除脑功功能缺失的研究计划任务书 附件1 项目编号: 大同煤矿集团有限责任公司 科研项目立项任务书 项目名称: 前颞叶切除对脑功能缺失的研究 开发机构: 神经外科 起止年月: 2011.1,2011.12 项目负责人: 黄 建 军 strengthen the sense of responsibility, work to solve the lack of decent occupation explain away, conduct problems. To establish the overall concept, eliminate departmentalism. Strict assessment and accountability, to solve the spiritual slack, nianqingpazhong, status quo, and other issues. To establish and perfect the muddle along Bureau staff conduct work regulations, standardize the behavior of personnel. 2. To strengthen the responsibility system. One is the in-depth study and implement the "Hunan provincial Party and government leading cadres Interim Provisions on the work safety of a pair of > (Hunan Office issued 2013 No. 5)," Hunan province safety supervision and management responsibilities of the provisions on the production (Hunan Zhengban made 2013 No. 4) And resolutely implement the safety production of the party with responsibility, a pair of responsibility. "Two is issued safety production administration and inspection to promote the responsibilities bear safety production supervision departments strictly and effectively assumed responsibility. The three is to establish risk self correction self reporting system for safety in production enterprises, promote the enterprises to implement the main responsibility for production safety is introduced. Four strengthen the county safety production supervision ability construction work, promote safe production responsibility to the grassroots. 3, strict accountability and target management. Adhere to the" who is in charge, who is responsible for the pipe industry must be safe, Guan Sheng production and operation must be safe, pipe business must control security "principle, the implementation of safety The production of "cure." stagnation supervision and leadership responsible system. The safety production of key towns, key enterprises and key problems, by the township government and the Department responsible for the stagnation led the lump sum, to tackle tough. To further increase the production safety index assessment, strictly implement the safety production of the "one vote veto" and the reward system, strengthen the safety incentive and restraint mechanism. (six) the implementation of the work force is not strong. The documents, meeting, long work arrangement, check and supervise the implementation of small, poor implementation of the system, the work is not effective. Some leading cadres sense of purpose, consciousness of the masses is not strong, the ruling " For the people "," the interests of the masses no matter "concept understanding is not in place. The specific work treats with the deployment, a few leading cadres complain that work is too complicated, too much responsibility, the pressure is too large, too much emphasis on the difficulty of the work, such as underground mines to avoid the disaster of" six systems "construction and construction of mechanical ventilation to file the form, forwarding arrangements work, no in-depth mining enterprises to promote the specific work, the increase in the number of files, but the effect is not good, not according to the actual situation of non coal mines in the county, to engage in" across the board ", and the quality 一、 立项的目的意义及必要性 前颞叶切除术(ALT)是一种有效的控制颞叶癫痫发作的方法，约70%-80%的患者术后效果满意，然而，神经认知方面的并发症，尤其是记忆能力的下降，仍然是手术治疗的一个显著而且相对常见的副作用。因此如何最大限度地既改善临床发作症状又能提高治愈率在临床工作中有重要意义。 手术切除了异常结构或异常放电的脑组织，消除或阻断了大脑内异常放电的形成，控制了癫痫发作，缓解了大脑缺氧造成的功能障碍，有利于患者智力及神经心理恢复，有助于癫痫手术方法的选择及疗效的判断有重要的意义。 因此，癫痫患者的治疗，除控制临床发作之外，对其智力及精神心理的关注也不能忽视，需要全社会的关爱。使患者置身于更温馨和谐的良好氛围中，对缓解病情，消除焦虑和情绪有很大的帮助，同时也增强了自我战胜疾病的信心。 癫痫发作的得到控制后，与周围人的沟通、交流更加广泛，参加社会活动越来越多，患者的自信心也越来越强，心理及精神压力也得到很大缓解，性格及精神状况得到很大改善，另外，越来越多人的认可，大家对患者的关爱及看待癫痫的眼光也不同以前，这也使患者更好融入社会大家庭中，更加促进患者心理状况的恢复。 safe production safety is introduced. Four strengthen the county safety production supervision ability construction work, promote self reporting system for safety in production enterprises, promote the enterprises to implement the main responsibility for ctionproduction supervision departments strictly and effectively assumed responsibility. The three is to establish risk self corre of responsibility. "Two is issued safety production administration and inspection to promote the responsibilities bear safetypair roduction (Hunan Zhengban made 2013 No. 4) And resolutely implement the safety production of the party with responsibility, aunan Office issued 2013 No. 5)," Hunan province safety supervision and management responsibilities of the provisions on the pa pair of > (Hdepth study and implement the "Hunan provincial Party and government leading cadres Interim Provisions on the work safety of -t work regulations, standardize the behavior of personnel. 2. To strengthen the responsibility system. One is the innducthe spiritual slack, nianqingpazhong, status quo, and other issues. To establish and perfect the muddle along Bureau staff co conduct problems. To establish the overall concept, eliminate departmentalism. Strict assessment and accountability, to solve strengthen the sense of responsibility, work to solve the lack of decent occupation explain away,and the qualityccording to the actual situation of non coal mines in the county, to engage in" across the board ", depth mining enterprises to promote the specific work, the increase in the number of files, but the effect is not good, not a-rding arrangements work, no inforwa ground mines to avoid the disaster of" six systems "construction and construction of mechanical ventilation to file the form,mplicated, too much responsibility, the pressure is too large, too much emphasis on the difficulty of the work, such as undertoo cocept understanding is not in place. The specific work treats with the deployment, a few leading cadres complain that work is urpose, consciousness of the masses is not strong, the ruling " For the people "," the interests of the masses no matter "cone of psupervise the implementation of small, poor implementation of the system, the work is not effective. Some leading cadres sensechanism. (six) the implementation of the work force is not strong. The documents, meeting, long work arrangement, check and aint mictly implement the safety production of the "one vote veto" and the reward system, strengthen the safety incentive and restronsible for the stagnation led the lump sum, to tackle tough. To further increase the production safety index assessment, strt resple system. The safety production of key towns, key enterprises and key problems, by the township government and the Departmenl security "principle, the implementation of safety The production of "cure." stagnation supervision and leadership responsibontrowho is responsible for the pipe industry must be safe, Guan Sheng production and operation must be safe, pipe business must c production responsibility to the grassroots. 3, strict accountability and target management. Adhere to the" who is in charge,- 2 - 二、主要研究目标和内容 通过对颞叶癫痫的患者的术前术后脑功能的评价，前颞叶切除术后脑功能状况，分析对其神经心理及智力状况进行探讨，对颞叶癫痫病人进行智力测定和神经心理学检查，不仅仅是为了判断这类病人智力减退和神经心理障碍的程度，更重要的是了解智力障碍和神经心理改变怀癫痫的关系，以及癫痫手术对其的影响，手术治疗是颞叶癫痫有效的治疗手段，此结论已被大量的临床结论所证实。通过探讨治疗前后患者精神心理及智力的变化，手术治疗不仅可以控制患者的临床症状的发作，而且对患者智力和精神心理障碍也能有不同程度的改善。同时有助于癫痫手术方法的选择及其疗效判断。 评价方法: 1(患者术前采用SCL-90自测量表对患者情绪程度、焦虑、抑郁和人际关系敏感进行评价，同时采用瑞文测验检测病人智力情况。手术后3个月复查，再次对心理状况和智力情况进行评分。 2(记忆测评:在术前一周，术后2周和术后6个月以后分别进行三次记忆测评。所用记忆量表为龚耀先教授修订的第二版(1989)《修订韦氏记忆量表》。术前测试用甲式，术后用乙式。根据各年龄段的量表，查找患者的量表分所对诮的MQ值。术前用药未做特殊要求。 3(分组比较:进行术前1周，术后2周和术后6个月时韦氏记忆评分的比较(包括:MQ、长时记忆、短时记忆、瞬间记忆)。比较左侧ATL组和右侧ATL组术前和术后2周是和项记忆评分的差异。根据患者病理检查有无海马硬化分组，比较两组术前术后记忆评分的差异，根据患者术前MQ值分为高分组(MQ?90分)和低分组MQ,90分〉根据术后患者记忆改变的程度分记忆减退组，MQ比术前基础分下降?10%)和记忆不 producself reporting system for safety in production enterprises, promote the enterprises to implement the main responsibility for tion supervision departments strictly and effectively assumed responsibility. The three is to establish risk self correction producf responsibility. "Two is issued safety production administration and inspection to promote the responsibilities bear safety on (Hunan Zhengban made 2013 No. 4) And resolutely implement the safety production of the party with responsibility, a pair oductian Office issued 2013 No. 5)," Hunan province safety supervision and management responsibilities of the provisions on the proimplement the "Hunan provincial Party and government leading cadres Interim Provisions on the work safety of a pair of > (Hun depth study and-work regulations, standardize the behavior of personnel. 2. To strengthen the responsibility system. One is the in piritual slack, nianqingpazhong, status quo, and other issues. To establish and perfect the muddle along Bureau staff conductish the overall concept, eliminate departmentalism. Strict assessment and accountability, to solve the sstrengthen the sense of responsibility, work to solve the lack of decent occupation explain away, conduct problems. To establnd the qualityffect is not good, not according to the actual situation of non coal mines in the county, to engage in" across the board ", adepth mining enterprises to promote the specific work, the increase in the number of files, but the e-ding arrangements work, no inmines to avoid the disaster of" six systems "construction and construction of mechanical ventilation to file the form, forwarround plicated, too much responsibility, the pressure is too large, too much emphasis on the difficulty of the work, such as undergderstanding is not in place. The specific work treats with the deployment, a few leading cadres complain that work is too comept unrpose, consciousness of the masses is not strong, the ruling " For the people "," the interests of the masses no matter "concse the implementation of small, poor implementation of the system, the work is not effective. Some leading cadres sense of puupervichanism. (six) the implementation of the work force is not strong. The documents, meeting, long work arrangement, check and smplement the safety production of the "one vote veto" and the reward system, strengthen the safety incentive and restraint mectly insible for the stagnation led the lump sum, to tackle tough. To further increase the production safety index assessment, striem. The safety production of key towns, key enterprises and key problems, by the township government and the Department resposyst security "principle, the implementation of safety The production of "cure." stagnation supervision and leadership responsibleresponsible for the pipe industry must be safe, Guan Sheng production and operation must be safe, pipe business must control who isroduction responsibility to the grassroots. 3, strict accountability and target management. Adhere to the" who is in charge, tion safety is introduced. Four strengthen the county safety production supervision ability construction work, promote safe p- 3 - 变和改善组(MQ下降不足10%或有所增加) 经济、社会效益 顽固性癫痫占癫痫的20%，而颞叶癫痫占其中的1/3;颞叶切除术治疗颞叶癫痫有效率达80%以上;然而，神经认知方面的并发症，尤其是记忆能力的下降，仍然是手术治疗的一个显著而且相对常见的副作用。探讨颞叶癫痫的手术治疗前后其神经心理及智力状况，全方位了解手术治疗对癫痫病人生活质量的改善，选择手术入路有重要的临床意义。对提高颞叶癫痫的手术疗效降低手术并发症以及树立患者生活的信心有积极的作用。 此项技术的应用为本省乃至周边地区的患者带来很大的社会经济效益，相应提高医院的诊治水平和经济收益。 开展此项治疗具有很高的技术价值。此项技术为病人在本地解除了痛苦，不必奔波外地大医院，收到了很好的社会效益。此项技术，在省内属领先技术，在同煤集团填补了空白。开展后会创造很好的社会和经济效益。 safe production safety is introduced. Four strengthen the county safety production supervision ability construction work, promote self reporting system for safety in production enterprises, promote the enterprises to implement the main responsibility for ctionproduction supervision departments strictly and effectively assumed responsibility. The three is to establish risk self corre of responsibility. "Two is issued safety production administration and inspection to promote the responsibilities bear safetypair roduction (Hunan Zhengban made 2013 No. 4) And resolutely implement the safety production of the party with responsibility, aunan Office issued 2013 No. 5)," Hunan province safety supervision and management responsibilities of the provisions on the pa pair of > (Hdepth study and implement the "Hunan provincial Party and government leading cadres Interim Provisions on the work safety of -t work regulations, standardize the behavior of personnel. 2. To strengthen the responsibility system. One is the innducthe spiritual slack, nianqingpazhong, status quo, and other issues. To establish and perfect the muddle along Bureau staff co conduct problems. To establish the overall concept, eliminate departmentalism. Strict assessment and accountability, to solve strengthen the sense of responsibility, work to solve the lack of decent occupation explain away,and the qualityccording to the actual situation of non coal mines in the county, to engage in" across the board ", depth mining enterprises to promote the specific work, the increase in the number of files, but the effect is not good, not a-rding arrangements work, no inforwa ground mines to avoid the disaster of" six systems "construction and construction of mechanical ventilation to file the form,mplicated, too much responsibility, the pressure is too large, too much emphasis on the difficulty of the work, such as undertoo cocept understanding is not in place. The specific work treats with the deployment, a few leading cadres complain that work is urpose, consciousness of the masses is not strong, the ruling " For the people "," the interests of the masses no matter "cone of psupervise the implementation of small, poor implementation of the system, the work is not effective. Some leading cadres sensechanism. (six) the implementation of the work force is not strong. The documents, meeting, long work arrangement, check and aint mictly implement the safety production of the "one vote veto" and the reward system, strengthen the safety incentive and restronsible for the stagnation led the lump sum, to tackle tough. To further increase the production safety index assessment, strt resple system. The safety production of key towns, key enterprises and key problems, by the township government and the Departmenl security "principle, the implementation of safety The production of "cure." stagnation supervision and leadership responsibontrowho is responsible for the pipe industry must be safe, Guan Sheng production and operation must be safe, pipe business must c production responsibility to the grassroots. 3, strict accountability and target management. Adhere to the" who is in charge,- 4 - 三、 采用的研究、试验方法和技术路线(包括工艺流程) 1(患者术前采用SCL-90自测量表对患者情绪程度、焦虑、抑郁和人际关系敏感进行评价，同时采用瑞文测验检测病人智力情况。手术后3个月复查，再次对心理状况和智力情况进行评分。 2(记忆测评:在术前一周，术后2周和术后6个月以后分别进行三次记忆测评。所用记忆量表为龚耀先教授修订的第二版(1989)《修订韦氏记忆量表》。术前测试用甲式，术后用乙式。根据各年龄段的量表，查找患者的量表分所对诮的MQ值。术前用药未做特殊要求。 3(分组比较:进行术前1周，术后2周和术后6个月时韦氏记忆评分的比较(包括:MQ、长时记忆、短时记忆、瞬间记忆)。比较左侧ATL组和右侧ATL组术前和术后2周是和项记忆评分的差异。根据患者病理检查有无海马硬化分组，比较两组术前术后记忆评分的差异，根据患者术前MQ值分为高分组(MQ?90分)和低分组MQ,90分〉根据术后患者记忆改变的程度分记忆减退组，MQ比术前基础分下降?10%)和记忆不变和改善组(MQ下降不足10%或有所增加) 114(H-MRS检查:术前进行氢质子磁共振波谱分析H-magneticresonance 1spectroscopy , H-MRS) 5.手术方式:所行ATL包括切除颞叶前部4.5cm(左侧)~5.5cm (右侧)，切除的组织送病检。 6.应用西门子SONATA 1.5T MRI分别进行不同的汉语语言听觉刺激任务 下的脑功能成像，汉语语言听觉任务分为二组:词汇理解组、段落理解 组。同时以音乐组作为单纯听觉刺激对照。图像资料经后处理获得脑区 who isroduction responsibility to the grassroots. 3, strict accountability and target management. Adhere to the" who is in charge, tion safety is introduced. Four strengthen the county safety production supervision ability construction work, promote safe pproducself reporting system for safety in production enterprises, promote the enterprises to implement the main responsibility for tion supervision departments strictly and effectively assumed responsibility. The three is to establish risk self correction producf responsibility. "Two is issued safety production administration and inspection to promote the responsibilities bear safety on (Hunan Zhengban made 2013 No. 4) And resolutely implement the safety production of the party with responsibility, a pair oductian Office issued 2013 No. 5)," Hunan province safety supervision and management responsibilities of the provisions on the proimplement the "Hunan provincial Party and government leading cadres Interim Provisions on the work safety of a pair of > (Hun depth study and-work regulations, standardize the behavior of personnel. 2. To strengthen the responsibility system. One is the in piritual slack, nianqingpazhong, status quo, and other issues. To establish and perfect the muddle along Bureau staff conductish the overall concept, eliminate departmentalism. Strict assessment and accountability, to solve the sstrengthen the sense of responsibility, work to solve the lack of decent occupation explain away, conduct problems. To establnd the qualityffect is not good, not according to the actual situation of non coal mines in the county, to engage in" across the board ", adepth mining enterprises to promote the specific work, the increase in the number of files, but the e-ding arrangements work, no inmines to avoid the disaster of" six systems "construction and construction of mechanical ventilation to file the form, forwarround plicated, too much responsibility, the pressure is too large, too much emphasis on the difficulty of the work, such as undergderstanding is not in place. The specific work treats with the deployment, a few leading cadres complain that work is too comept unrpose, consciousness of the masses is not strong, the ruling " For the people "," the interests of the masses no matter "concse the implementation of small, poor implementation of the system, the work is not effective. Some leading cadres sense of puupervichanism. (six) the implementation of the work force is not strong. The documents, meeting, long work arrangement, check and smplement the safety production of the "one vote veto" and the reward system, strengthen the safety incentive and restraint mectly insible for the stagnation led the lump sum, to tackle tough. To further increase the production safety index assessment, striem. The safety production of key towns, key enterprises and key problems, by the township government and the Department resposyst security "principle, the implementation of safety The production of "cure." stagnation supervision and leadership responsibleresponsible for the pipe industry must be safe, Guan Sheng production and operation must be safe, pipe business must control - 5 - 激活图Wernicke区的功能定位 激活图。以定位Wernicke区。 五、现有技术基础及条件 1、现有拥有的人才。 2、经费保障: 3、拥有的硬件资源: 4、利用的外部资源: 难治性占癫痫的20%,其中以颞叶癫痫又占难治性癫痫的1/3;前颞叶切除术作为治疗颞叶癫痫的主要的术式，在治疗颞叶癫痫中起到了重要的作有用，随着显微神经外科技术的发展，电生理理技术的进步，以及神经影像技术的成熟，越来越多的颞叶癫痫得到早期诊断，以住都是保守治疗，手术作为唯一根治方法，但是颞叶的功能越来越受到重视，术后并发许多并发症，例如双侧颞叶切除术后出现严重的记忆障碍，给家庭和社会带来许多负担。我们有责任对颞叶功能作一更深入的了解，对颞叶损伤以及颞叶切除术最大可能保护颞叶重要功能有着重要的意义。神经外科开展此项研究具有很高的实用价值。在具体的研究过程中，我院同北京三博脑科医院，北京天坛医院等各大医院的功能神经外科合作，同时也派出我科的技术以及业务骨干出去学习，使我们的工作逐步完善。 ontrowho is responsible for the pipe industry must be safe, Guan Sheng production and operation must be safe, pipe business must c production responsibility to the grassroots. 3, strict accountability and target management. Adhere to the" who is in charge,safe production safety is introduced. Four strengthen the county safety production supervision ability construction work, promote self reporting system for safety in production enterprises, promote the enterprises to implement the main responsibility for ctionproduction supervision departments strictly and effectively assumed responsibility. The three is to establish risk self corre of responsibility. "Two is issued safety production administration and inspection to promote the responsibilities bear safetypair roduction (Hunan Zhengban made 2013 No. 4) And resolutely implement the safety production of the party with responsibility, aunan Office issued 2013 No. 5)," Hunan province safety supervision and management responsibilities of the provisions on the pa pair of > (Hdepth study and implement the "Hunan provincial Party and government leading cadres Interim Provisions on the work safety of -t work regulations, standardize the behavior of personnel. 2. To strengthen the responsibility system. One is the innducthe spiritual slack, nianqingpazhong, status quo, and other issues. To establish and perfect the muddle along Bureau staff co conduct problems. To establish the overall concept, eliminate departmentalism. Strict assessment and accountability, to solve strengthen the sense of responsibility, work to solve the lack of decent occupation explain away,and the qualityccording to the actual situation of non coal mines in the county, to engage in" across the board ", depth mining enterprises to promote the specific work, the increase in the number of files, but the effect is not good, not a-rding arrangements work, no inforwa ground mines to avoid the disaster of" six systems "construction and construction of mechanical ventilation to file the form,mplicated, too much responsibility, the pressure is too large, too much emphasis on the difficulty of the work, such as undertoo cocept understanding is not in place. The specific work treats with the deployment, a few leading cadres complain that work is urpose, consciousness of the masses is not strong, the ruling " For the people "," the interests of the masses no matter "cone of psupervise the implementation of small, poor implementation of the system, the work is not effective. Some leading cadres sensechanism. (six) the implementation of the work force is not strong. The documents, meeting, long work arrangement, check and aint mictly implement the safety production of the "one vote veto" and the reward system, strengthen the safety incentive and restronsible for the stagnation led the lump sum, to tackle tough. To further increase the production safety index assessment, strt resple system. The safety production of key towns, key enterprises and key problems, by the township government and the Departmenl security "principle, the implementation of safety The production of "cure." stagnation supervision and leadership responsib- 6 - 六、进度安排 ,.业务:分批前往北京三博脑科医院技术中心学习。 ,.技术研发:科题主要负责科研项目整体的设计、实施、技术路线、数据分析、论文撰写、申请课题鉴定等等，并负责与技术顾问的沟通和关键技术的把握。 3(年底结题，写出总结，申报科研成果。 七、承担单位和主要协作单位及分工 tion safety is introduced. Four strengthen the county safety production supervision ability construction work, promote safe pproducself reporting system for safety in production enterprises, promote the enterprises to implement the main responsibility for tion supervision departments strictly and effectively assumed responsibility. The three is to establish risk self correction producf responsibility. "Two is issued safety production administration and inspection to promote the responsibilities bear safety on (Hunan Zhengban made 2013 No. 4) And resolutely implement the safety production of the party with responsibility, a pair oductian Office issued 2013 No. 5)," Hunan province safety supervision and management responsibilities of the provisions on the proimplement the "Hunan provincial Party and government leading cadres Interim Provisions on the work safety of a pair of > (Hun depth study and-work regulations, standardize the behavior of personnel. 2. To strengthen the responsibility system. One is the in piritual slack, nianqingpazhong, status quo, and other issues. To establish and perfect the muddle along Bureau staff conductish the overall concept, eliminate departmentalism. Strict assessment and accountability, to solve the sstrengthen the sense of responsibility, work to solve the lack of decent occupation explain away, conduct problems. To establnd the qualityffect is not good, not according to the actual situation of non coal mines in the county, to engage in" across the board ", adepth mining enterprises to promote the specific work, the increase in the number of files, but the e-ding arrangements work, no inmines to avoid the disaster of" six systems "construction and construction of mechanical ventilation to file the form, forwarround plicated, too much responsibility, the pressure is too large, too much emphasis on the difficulty of the work, such as undergderstanding is not in place. The specific work treats with the deployment, a few leading cadres complain that work is too comept unrpose, consciousness of the masses is not strong, the ruling " For the people "," the interests of the masses no matter "concse the implementation of small, poor implementation of the system, the work is not effective. Some leading cadres sense of puupervichanism. (six) the implementation of the work force is not strong. The documents, meeting, long work arrangement, check and smplement the safety production of the "one vote veto" and the reward system, strengthen the safety incentive and restraint mectly insible for the stagnation led the lump sum, to tackle tough. To further increase the production safety index assessment, striem. The safety production of key towns, key enterprises and key problems, by the township government and the Department resposyst security "principle, the implementation of safety The production of "cure." stagnation supervision and leadership responsibleresponsible for the pipe industry must be safe, Guan Sheng production and operation must be safe, pipe business must control who isroduction responsibility to the grassroots. 3, strict accountability and target management. Adhere to the" who is in charge, - 7 - 八(项目研究人员名单 姓 名 性别 部门 职称或职务 承担内容 负责人 黄建军 男 神经外科 业务副院长 王 勇 男 神经外科 副主任 男 神经外科 武日富 主任医师 男 神经外科 白永文 主任医师 男 神经外科 马 喜 副主任医师 男 神经外科 马 东 副主任医师 项 男 神经外科 李力波 主治医师 目 男 神经外科 张国清 主治医师 主 男 神经外科 马 彤 主治医师 要 男 神经外科 韩光迅 主治医师 参 男 神经外科 王俊平 医 师 男 神经外科 张素清 医 师 加 男 神经外科 王永平 主治医师 人 配合 神经外科 人数 onsible for the stagnation led the lump sum, to tackle tough. To further increase the production safety index assessment, strt resple system. The safety production of key towns, key enterprises and key problems, by the township government and the Departmenl security "principle, the implementation of safety The production of "cure." stagnation supervision and leadership responsibontrowho is responsible for the pipe industry must be safe, Guan Sheng production and operation must be safe, pipe business must c production responsibility to the grassroots. 3, strict accountability and target management. Adhere to the" who is in charge,safe production safety is introduced. Four strengthen the county safety production supervision ability construction work, promote self reporting system for safety in production enterprises, promote the enterprises to implement the main responsibility for ctionproduction supervision departments strictly and effectively assumed responsibility. The three is to establish risk self corre of responsibility. "Two is issued safety production administration and inspection to promote the responsibilities bear safetypair roduction (Hunan Zhengban made 2013 No. 4) And resolutely implement the safety production of the party with responsibility, aunan Office issued 2013 No. 5)," Hunan province safety supervision and management responsibilities of the provisions on the pa pair of > (Hdepth study and implement the "Hunan provincial Party and government leading cadres Interim Provisions on the work safety of -t work regulations, standardize the behavior of personnel. 2. To strengthen the responsibility system. One is the innducthe spiritual slack, nianqingpazhong, status quo, and other issues. To establish and perfect the muddle along Bureau staff co conduct problems. To establish the overall concept, eliminate departmentalism. Strict assessment and accountability, to solve strengthen the sense of responsibility, work to solve the lack of decent occupation explain away,and the qualityccording to the actual situation of non coal mines in the county, to engage in" across the board ", depth mining enterprises to promote the specific work, the increase in the number of files, but the effect is not good, not a-rding arrangements work, no inforwa ground mines to avoid the disaster of" six systems "construction and construction of mechanical ventilation to file the form,mplicated, too much responsibility, the pressure is too large, too much emphasis on the difficulty of the work, such as undertoo cocept understanding is not in place. The specific work treats with the deployment, a few leading cadres complain that work is urpose, consciousness of the masses is not strong, the ruling " For the people "," the interests of the masses no matter "cone of psupervise the implementation of small, poor implementation of the system, the work is not effective. Some leading cadres sensechanism. (six) the implementation of the work force is not strong. The documents, meeting, long work arrangement, check and aint mictly implement the safety production of the "one vote veto" and the reward system, strengthen the safety incentive and restr- 8 - 九、项目用到的及需要增添的主要设备、仪器、材料 项目用到的设备、仪器、材料: 需要增加的设备、仪器、材料: 1 11(购置氢质子磁共振波谱分析H-magneticresonance spectroscopy , H-MRS)软件。。 2( 购置fMRI功能定位软件; 十、经费总概算 费用名称 金额(万元) 合作费 10万元人民币 设备购置费 30万元人民币 经费 总概算 培训费 5万元人民币 科研费 5万元人民币 合 计 chanism. (six) the implementation of the work force is not strong. The documents, meeting, long work arrangement, check and smplement the safety production of the "one vote veto" and the reward system, strengthen the safety incentive and restraint mectly insible for the stagnation led the lump sum, to tackle tough. To further increase the production safety index assessment, striem. The safety production of key towns, key enterprises and key problems, by the township government and the Department resposyst security "principle, the implementation of safety The production of "cure." stagnation supervision and leadership responsibleresponsible for the pipe industry must be safe, Guan Sheng production and operation must be safe, pipe business must control who isroduction responsibility to the grassroots. 3, strict accountability and target management. Adhere to the" who is in charge, tion safety is introduced. Four strengthen the county safety production supervision ability construction work, promote safe pproducself reporting system for safety in production enterprises, promote the enterprises to implement the main responsibility for tion supervision departments strictly and effectively assumed responsibility. The three is to establish risk self correction producf responsibility. "Two is issued safety production administration and inspection to promote the responsibilities bear safety on (Hunan Zhengban made 2013 No. 4) And resolutely implement the safety production of the party with responsibility, a pair oductian Office issued 2013 No. 5)," Hunan province safety supervision and management responsibilities of the provisions on the proimplement the "Hunan provincial Party and government leading cadres Interim Provisions on the work safety of a pair of > (Hun depth study and-work regulations, standardize the behavior of personnel. 2. To strengthen the responsibility system. One is the in piritual slack, nianqingpazhong, status quo, and other issues. To establish and perfect the muddle along Bureau staff conductish the overall concept, eliminate departmentalism. Strict assessment and accountability, to solve the sstrengthen the sense of responsibility, work to solve the lack of decent occupation explain away, conduct problems. To establnd the qualityffect is not good, not according to the actual situation of non coal mines in the county, to engage in" across the board ", adepth mining enterprises to promote the specific work, the increase in the number of files, but the e-ding arrangements work, no inmines to avoid the disaster of" six systems "construction and construction of mechanical ventilation to file the form, forwarround plicated, too much responsibility, the pressure is too large, too much emphasis on the difficulty of the work, such as undergderstanding is not in place. The specific work treats with the deployment, a few leading cadres complain that work is too comept unrpose, consciousness of the masses is not strong, the ruling " For the people "," the interests of the masses no matter "concse the implementation of small, poor implementation of the system, the work is not effective. Some leading cadres sense of puupervi- 9 - 十一、经费支出明细预算表 预算费用分年度预算金额(万元) 费用名称 (万元) 2009年 2010年 2011年 科研人工费 科研用固定资产折旧 科研用材料、备品备件与半成品 试验试制费 科研开发人员差旅费 开发人员培训费 科研用图书资料费 关键科研仪器设备摊销(30万) 科研开发机构办公费 科研开发设备租赁费 项目验收鉴定成果登记等费用 委外科研开发费 与技术开发相关其他费用 合 计 self reporting system for safety in production enterprises, promote the enterprises to implement the main responsibility for ctionproduction supervision departments strictly and effectively assumed responsibility. The three is to establish risk self corre of responsibility. "Two is issued safety production administration and inspection to promote the responsibilities bear safetypair roduction (Hunan Zhengban made 2013 No. 4) And resolutely implement the safety production of the party with responsibility, aunan Office issued 2013 No. 5)," Hunan province safety supervision and management responsibilities of the provisions on the pa pair of > (Hdepth study and implement the "Hunan provincial Party and government leading cadres Interim Provisions on the work safety of -t work regulations, standardize the behavior of personnel. 2. To strengthen the responsibility system. One is the innducthe spiritual slack, nianqingpazhong, status quo, and other issues. To establish and perfect the muddle along Bureau staff co conduct problems. To establish the overall concept, eliminate departmentalism. Strict assessment and accountability, to solve strengthen the sense of responsibility, work to solve the lack of decent occupation explain away,and the qualityccording to the actual situation of non coal mines in the county, to engage in" across the board ", depth mining enterprises to promote the specific work, the increase in the number of files, but the effect is not good, not a-rding arrangements work, no inforwa ground mines to avoid the disaster of" six systems "construction and construction of mechanical ventilation to file the form,mplicated, too much responsibility, the pressure is too large, too much emphasis on the difficulty of the work, such as undertoo cocept understanding is not in place. The specific work treats with the deployment, a few leading cadres complain that work is urpose, consciousness of the masses is not strong, the ruling " For the people "," the interests of the masses no matter "cone of psupervise the implementation of small, poor implementation of the system, the work is not effective. Some leading cadres sensechanism. (six) the implementation of the work force is not strong. The documents, meeting, long work arrangement, check and aint mictly implement the safety production of the "one vote veto" and the reward system, strengthen the safety incentive and restronsible for the stagnation led the lump sum, to tackle tough. To further increase the production safety index assessment, strt resple system. The safety production of key towns, key enterprises and key problems, by the township government and the Departmenl security "principle, the implementation of safety The production of "cure." stagnation supervision and leadership responsibontrowho is responsible for the pipe industry must be safe, Guan Sheng production and operation must be safe, pipe business must c production responsibility to the grassroots. 3, strict accountability and target management. Adhere to the" who is in charge,safe production safety is introduced. Four strengthen the county safety production supervision ability construction work, promote - 10 - 十二、技术的先进性与技术资料 技术先进性: 技术资料: 十三、技术成果与形式 tion safety is introduced. Four strengthen the county safety production supervision ability construction work, promote safe pproducself reporting system for safety in production enterprises, promote the enterprises to implement the main responsibility for tion supervision departments strictly and effectively assumed responsibility. The three is to establish risk self correction producf responsibility. "Two is issued safety production administration and inspection to promote the responsibilities bear safety on (Hunan Zhengban made 2013 No. 4) And resolutely implement the safety production of the party with responsibility, a pair oductian Office issued 2013 No. 5)," Hunan province safety supervision and management responsibilities of the provisions on the proimplement the "Hunan provincial Party and government leading cadres Interim Provisions on the work safety of a pair of > (Hun depth study and-work regulations, standardize the behavior of personnel. 2. To strengthen the responsibility system. One is the in piritual slack, nianqingpazhong, status quo, and other issues. To establish and perfect the muddle along Bureau staff conductish the overall concept, eliminate departmentalism. Strict assessment and accountability, to solve the sstrengthen the sense of responsibility, work to solve the lack of decent occupation explain away, conduct problems. To establnd the qualityffect is not good, not according to the actual situation of non coal mines in the county, to engage in" across the board ", adepth mining enterprises to promote the specific work, the increase in the number of files, but the e-ding arrangements work, no inmines to avoid the disaster of" six systems "construction and construction of mechanical ventilation to file the form, forwarround plicated, too much responsibility, the pressure is too large, too much emphasis on the difficulty of the work, such as undergderstanding is not in place. The specific work treats with the deployment, a few leading cadres complain that work is too comept unrpose, consciousness of the masses is not strong, the ruling " For the people "," the interests of the masses no matter "concse the implementation of small, poor implementation of the system, the work is not effective. Some leading cadres sense of puupervichanism. (six) the implementation of the work force is not strong. The documents, meeting, long work arrangement, check and smplement the safety production of the "one vote veto" and the reward system, strengthen the safety incentive and restraint mectly insible for the stagnation led the lump sum, to tackle tough. To further increase the production safety index assessment, striem. The safety production of key towns, key enterprises and key problems, by the township government and the Department resposyst security "principle, the implementation of safety The production of "cure." stagnation supervision and leadership responsibleresponsible for the pipe industry must be safe, Guan Sheng production and operation must be safe, pipe business must control who isroduction responsibility to the grassroots. 3, strict accountability and target management. Adhere to the" who is in charge, - 11 - 十四、申报单位意见 负责人(签名、盖章) 年 月 日 十五、部门审查意见 负责人(签名、盖章) 年 月 日 十六、公司专业技术领导审查意见 负责人(签名、盖章) 年 月 日 十七、集团公司审查意见 负责人(签名、盖章) 年 月 日 十八、上级部门审查意见 负责人(签名、盖章) 年 月 日 ictly implement the safety production of the "one vote veto" and the reward system, strengthen the safety incentive and restronsible for the stagnation led the lump sum, to tackle tough. To further increase the production safety index assessment, strt resple system. The safety production of key towns, key enterprises and key problems, by the township government and the Departmenl security "principle, the implementation of safety The production of "cure." stagnation supervision and leadership responsibontrowho is responsible for the pipe industry must be safe, Guan Sheng production and operation must be safe, pipe business must c production responsibility to the grassroots. 3, strict accountability and target management. Adhere to the" who is in charge,safe production safety is introduced. Four strengthen the county safety production supervision ability construction work, promote self reporting system for safety in production enterprises, promote the enterprises to implement the main responsibility for ctionproduction supervision departments strictly and effectively assumed responsibility. The three is to establish risk self corre of responsibility. "Two is issued safety production administration and inspection to promote the responsibilities bear safetypair roduction (Hunan Zhengban made 2013 No. 4) And resolutely implement the safety production of the party with responsibility, aunan Office issued 2013 No. 5)," Hunan province safety supervision and management responsibilities of the provisions on the pa pair of > (Hdepth study and implement the "Hunan provincial Party and government leading cadres Interim Provisions on the work safety of -t work regulations, standardize the behavior of personnel. 2. To strengthen the responsibility system. One is the innducthe spiritual slack, nianqingpazhong, status quo, and other issues. To establish and perfect the muddle along Bureau staff co conduct problems. To establish the overall concept, eliminate departmentalism. Strict assessment and accountability, to solve strengthen the sense of responsibility, work to solve the lack of decent occupation explain away,and the qualityccording to the actual situation of non coal mines in the county, to engage in" across the board ", depth mining enterprises to promote the specific work, the increase in the number of files, but the effect is not good, not a-rding arrangements work, no inforwa ground mines to avoid the disaster of" six systems "construction and construction of mechanical ventilation to file the form,mplicated, too much responsibility, the pressure is too large, too much emphasis on the difficulty of the work, such as undertoo cocept understanding is not in place. The specific work treats with the deployment, a few leading cadres complain that work is urpose, consciousness of the masses is not strong, the ruling " For the people "," the interests of the masses no matter "cone of psupervise the implementation of small, poor implementation of the system, the work is not effective. Some leading cadres sensechanism. (six) the implementation of the work force is not strong. The documents, meeting, long work arrangement, check and aint m- 12 - 附件2: “可行性”提纲 1、项目概要 2、目的与意义 3、国内外概况、发展趋势 4、前期科研工作情况、现有基础和条件(已做的工作和具备的科研条 件) 5、科技项目目标 6、技术经费预计(分析) 7、实施方法及进度安排 8、经济社会效益 9、项目风险性分析及对策 security "principle, the implementation of safety The production of "cure." stagnation supervision and leadership responsibleresponsible for the pipe industry must be safe, Guan Sheng production and operation must be safe, pipe business must control who isroduction responsibility to the grassroots. 3, strict accountability and target management. Adhere to the" who is in charge, tion safety is introduced. Four strengthen the county safety production supervision ability construction work, promote safe pproducself reporting system for safety in production enterprises, promote the enterprises to implement the main responsibility for tion supervision departments strictly and effectively assumed responsibility. The three is to establish risk self correction producf responsibility. "Two is issued safety production administration and inspection to promote the responsibilities bear safety on (Hunan Zhengban made 2013 No. 4) And resolutely implement the safety production of the party with responsibility, a pair oductian Office issued 2013 No. 5)," Hunan province safety supervision and management responsibilities of the provisions on the proimplement the "Hunan provincial Party and government leading cadres Interim Provisions on the work safety of a pair of > (Hun depth study and-work regulations, standardize the behavior of personnel. 2. To strengthen the responsibility system. One is the in piritual slack, nianqingpazhong, status quo, and other issues. To establish and perfect the muddle along Bureau staff conductish the overall concept, eliminate departmentalism. Strict assessment and accountability, to solve the sstrengthen the sense of responsibility, work to solve the lack of decent occupation explain away, conduct problems. To establnd the qualityffect is not good, not according to the actual situation of non coal mines in the county, to engage in" across the board ", adepth mining enterprises to promote the specific work, the increase in the number of files, but the e-ding arrangements work, no inmines to avoid the disaster of" six systems "construction and construction of mechanical ventilation to file the form, forwarround plicated, too much responsibility, the pressure is too large, too much emphasis on the difficulty of the work, such as undergderstanding is not in place. The specific work treats with the deployment, a few leading cadres complain that work is too comept unrpose, consciousness of the masses is not strong, the ruling " For the people "," the interests of the masses no matter "concse the implementation of small, poor implementation of the system, the work is not effective. Some leading cadres sense of puupervichanism. (six) the implementation of the work force is not strong. The documents, meeting, long work arrangement, check and smplement the safety production of the "one vote veto" and the reward system, strengthen the safety incentive and restraint mectly insible for the stagnation led the lump sum, to tackle tough. To further increase the production safety index assessment, striem. The safety production of key towns, key enterprises and key problems, by the township government and the Department resposyst - 13 - 附件3: 申报2010年同煤集团科研计划项目汇总表 申报单位 单位:万元 计划金额 序项目名称 项目简介 实施地 负责人 备注 装备与号 研究 仪器 工程 内镜下硬化剂治疗食管内镜下硬化剂、套扎术、组织胶注射 5 30 吴富 胃底静脉曲张 治疗食管胃底静脉曲张 合计 strengthen the sense of responsibility, work to solve the lack of decent occupation explain away, conduct problems. To establish the overall concept, eliminate departmentalism. Strict assessment and accountability, to solve the spiritual slack, nianqingpazhong, status quo, and other issues. To establish and perfect the muddle along Bureau staff conduct work regulations, standardize the behavior of personnel. 2. To strengthen the responsibility system. One is the in-depth study and implement the "Hunan provincial Party and government leading cadres Interim Provisions on the work safety of a pair of > (Hunan Office issued 2013 No. 5)," Hunan province safety supervision and management responsibilities of the provisions on the production (Hunan Zhengban made 2013 No. 4) And resolutely implement the safety production of the party with responsibility, a pair of responsibility. "Two is issued safety production administration and inspection to promote the responsibilities bear safety production supervision departments strictly and effectively assumed responsibility. The three is to establish risk self correction self reporting system for safety in production enterprises, promote the enterprises to implement the main responsibility for production safety is introduced. Four strengthen the county safety production supervision ability construction work, promote safe production responsibility to the grassroots. 3, strict accountability and target management. Adhere to the" who is in charge, who is responsible for the pipe industry must be safe, Guan Sheng production and operation must be safe, pipe business must control security "principle, the implementation of safety The production of "cure." stagnation supervision and leadership responsible system. The safety production of key towns, key enterprises and key problems, by the township government and the Department responsible for the stagnation led the lump sum, to tackle tough. To further increase the production safety index assessment, strictly implement the safety production of the "one vote veto" and the reward system, strengthen the safety incentive and restraint mechanism. (six) the implementation of the work force is not strong. The documents, meeting, long work arrangement, check and supervise the implementation of small, poor implementation of the system, the work is not effective. Some leading cadres sense of purpose, consciousness of the masses is not strong, the ruling " For the people "," the interests of the masses no matter "concept understanding is not in place. The specific work treats with the deployment, a few leading cadres complain that work is too complicated, too much responsibility, the pressure is too large, too much emphasis on the difficulty of the work, such as underground mines to avoid the disaster of" six systems "construction and construction of mechanical ventilation to file the form, forwarding arrangements work, no in-depth mining enterprises to promote the specific work, the increase in the number of files, but the effect is not good, not according to the actual situation of non coal mines in the county, to engage in" across the board ", and the quality security "principle, the implementation of safety The production of "cure." stagnation supervision and leadership responsibleresponsible for the pipe industry must be safe, Guan Sheng production and operation must be safe, pipe business must control who isroduction responsibility to the grassroots. 3, strict accountability and target management. Adhere to the" who is in charge, tion safety is introduced. Four strengthen the county safety production supervision ability construction work, promote safe pproducself reporting system for safety in production enterprises, promote the enterprises to implement the main responsibility for tion supervision departments strictly and effectively assumed responsibility. The three is to establish risk self correction producf responsibility. "Two is issued safety production administration and inspection to promote the responsibilities bear safety on (Hunan Zhengban made 2013 No. 4) And resolutely implement the safety production of the party with responsibility, a pair oductian Office issued 2013 No. 5)," Hunan province safety supervision and management responsibilities of the provisions on the proimplement the "Hunan provincial Party and government leading cadres Interim Provisions on the work safety of a pair of > (Hun depth study and-work regulations, standardize the behavior of personnel. 2. To strengthen the responsibility system. One is the in piritual slack, nianqingpazhong, status quo, and other issues. To establish and perfect the muddle along Bureau staff conductish the overall concept, eliminate departmentalism. Strict assessment and accountability, to solve the sstrengthen the sense of responsibility, work to solve the lack of decent occupation explain away, conduct problems. To establnd the qualityffect is not good, not according to the actual situation of non coal mines in the county, to engage in" across the board ", adepth mining enterprises to promote the specific work, the increase in the number of files, but the e-ding arrangements work, no inmines to avoid the disaster of" six systems "construction and construction of mechanical ventilation to file the form, forwarround plicated, too much responsibility, the pressure is too large, too much emphasis on the difficulty of the work, such as undergderstanding is not in place. The specific work treats with the deployment, a few leading cadres complain that work is too comept unrpose, consciousness of the masses is not strong, the ruling " For the people "," the interests of the masses no matter "concse the implementation of small, poor implementation of the system, the work is not effective. Some leading cadres sense of puupervichanism. (six) the implementation of the work force is not strong. The documents, meeting, long work arrangement, check and smplement the safety production of the "one vote veto" and the reward system, strengthen the safety incentive and restraint mectly insible for the stagnation led the lump sum, to tackle tough. To further increase the production safety index assessment, striem. The safety production of key towns, key enterprises and key problems, by the township government and the Department resposyst 1