[doc格式] “脑电超慢涨落图技术”在非屏蔽室内检测人脑神经递质分布的重测信度
“脑电超慢涨落图技术”在非屏蔽室内检测
人脑神经递质分布的重测信度
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[?????h??]100925934(2008)2032131203W?[???L?]???3]W?AW?[?q???[????]W?R741.044;R742
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W?W?[??W???]W?????:?(??oi?7?C???????x?????Ioa?H?????x???????????7?????.?H?[?(???????m,?d??
???????????H????W,????:?HW9?q??????????????W5???0??21?2?????????;,?H?????x??oi?7?C???????x
?[????oa?K??????????,??????????W990???????;??W5;5d?8???H?4???????H?4?j?????5?????fW,????:
?H?<?8?p?f?????q,???o?????;???[???3??W990???????;??W5??????11???]?]?q???????h?/???W?-??
????,?4oi?7?C???????x?[????oa??????9?N?????.?H?[?(?]?]???????W?-
????????W,????:???????H??
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Thetest2retestreliabilityofanoiencephalofluctuographyoaapparatusdetectingthehuman
brainneurotransmitterdistributioninanon2electromagneticshieldroom
HUANGZhiqiang,LINing,WANGJie.
NavalMedicalResearchInstituteNo.2MilitaryMedicalUniversity,Shanghai200433,China
[Abstract]W?Objective:Toevaluatethereliabilityofoiencephalofluctuographyoa(EFG)apparatusde2
tectingthehumanbrainneurotransmitterdistributioninaroomwithoutelectromagneticshield.Methods:
Twenty2onehealthysubjectsrecruitedthroughtheChinesePsychosomaticHealthScaleweretestedwith
theSymptomChecklist290(SCL290),andthendetectedwiththeEFGapparatusinaroomwithoutelec2
tromagneticshield.TheSCL290testandEFGexaminationwereconductedagain5dayslateraccordingto
thesamesequence.Results:TenofelevenindicantsfromSCL290,reflectingthesubjectsosstateofmind,
showedsignificantcorrelationinthetest-reteststudy;whilenoneoftheninein
dicantsaboutneuro2
transmitterdistributionfromtheapparatuswassignificantlycorrelated.Conc
lusion:TheEFGapparatus
isnotreliabletodetecttheneurotransmitterdistributioninthebrain,ifitisoper
atedinaroomwithout
electromagneticshield.
[Keywords]W?Encephalofluctuography(EFG);Neurotransmitter;Chines
ePsychosomaticHealth
Scale
W?W??7?C???x?????I(Encephalofluctuography,
EFG,????oi?7EToa)[1]
??20?h??80???????y???q
?????d???B
[2]
,?????r???r????W3?????5W3?????g??
?r?????J?[??,?(???7?C???q??oi???????x?R?[oa,?r
???????w?)?[,???????l?m?W???o(?2(GA2
BA)W3?j?H??(Glu)W352(52HT)W3????????
(Ach)W3???v???9???o(NE)W3?r????(DA)?>?r???7
?????.?H???????G?????????7????????,?4??????
???.?H???????y?l?k??????,???????o?????;????
?????[???3
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,?H?P???????-?w???????????H????W,
EFG???I???y????,?????H?2??????,?0?r??
?????F?????????I?d????oi?7?C???????x?[????oaW3
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??3??
?S???????C?y?[???6??,2008??6?1,?Z17???Z3?y1JournalofClinicalElec
troneurophysiology(China),June2008,Vol.17,No.3W?W?
W?W?
:2008-0-11
:2004:
2100102
0
1911
11
17?2,???m13?2W,????21??33??W,
???H???????y????oi?7?C???????x?[????oa,??
???2?????;????EFG????(??????30min),????
EFG???????H?????????w????W9?q????????????
??W5
[9]
??W990???????;??W5(SCL290)[10]
W,W9?q??????
????????W5???H?Z???f??????????,?H???E???????;
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?Z???f?????8?Z???f????????5?UW,?H?Z???f????
?q,?????;?????????????????8?Z???f????W,
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?2???k?0???h????W3????????W3????W3?y???8???[??W3
???????????????????????;,???521?2?????????;
????????W,
2.2W?SCL290??????????
?HQodQ??????,????SCL290???m?r???]?]
?????????????2?<???3?[?(,?B???H?(??SCL290
?p?f????????????????????,???HSpearman?>??
????W,????1????,SCL290????1???????p?f????
??????????(????????)?I????????,???w?p?f????
???????;?????[???3???Z???4W,??????????1W,
??1W?SCL290?p?f??????????????(n=21)
?]?]
????????(M(QR))(1)
?Z???f?Z???f
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??((?)
P
?P?[W?W?9.00(18.00)7.00(9.50)0.7890.000
?????hW?0.08(0.16)0.00(0.04)0.3610.108
?w??W?W?0.20(0.20)0.10(0.30)0.6200.003
???=????0.11(0.33)0.00(0.22)0.7640.000
????W?W?0.08(0.31)0.08(0.15)0.7130.000
?g??W?W?0.10(0.20)0.00(0.10)0.7770.000
????W?W?0.00(0.25)0.00(0.17)0.7360.000
???hW?W?0.00(0.07)0.00(0.14)0.9170.000
????W?W?0.00(0117)0.00(0.17)0.4540.000
???????m0.00(0.10)0.00(0.10)0.6940.000
????W?W?0.14(0.29)0.14(0.21)0.4330.050
W?W???:(1)???????3?[?(?Q???????/?S?????[??????,M?w?q??
??,QR=Q3odQ1,Q1??Q3?[?G?w?Z?????Z?0???[????
2.3W???EFG????????oi?????.?H?[?(oa??????????
???5QodQ???8,?????3?[?(??FG?]?]????
????????,?????????3?[?(??FG?]?]??
??Spearman?>??????(????2)W,????,?HEFG??
?p?f?????????q,???0???N?]?]?I?-??????????W,
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?]?]W?
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(1)
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P
GABA6.76??3.823.95??3.630.0750.747
GA3.33??3.293.43??4.200.1950.396
AChR29.43??6.8631.38??7.81-0.2700.236
52HT22.00(6.50)20.00(8.00)0.0430.852
ACh15.71??7.4120.76??9.77-0.1160.618
oi?w????oa15.38??6.4413.14??6.280.1830.428
NE11.00(3.50)9.00(7.00)-0.4750.029
DA7.00(6.50)6.00(6.50)-0.0640.782
oi?????Ooa6.71??3.995.95??3.440.2210.336
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?S???????C?y?[???6??,2008??6?1,?Z17???Z3?y1JournalofClinicalElec
troneurophysiology(China),June2008,Vol.17,No.3W?W?
W?W?
E
PearsonE10
21
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CMCT?????P???,?E
f???15(37.5)0(0)18(45.0)2(5.0)10(25.0)0(0)0(0)18(45.0)W?
f???7(22.5)0(0)15(48.3)5(19)W?22(70.9)(1)
9(29.3)W?24(77.4)(1)
26(83.8)(1)
f???0(0)0(0)0(0)0(0)12(23.5)18(35.2)20(39.2)30(58.8)
(2)
?P??22(18.0)0(0)33(27.0)7(5.7)44(36.0)27(22.0)44(36.0)74(60.7)(3)
W?W???:Ampf????w???=????,PLf????w???A?y????(?G???????A?y??????),CMCT?w???6PL?8T12PL?????kW,%???w???B?????G??????
???[??W,(1)???w??(?2
????,?8???p??????????????,P<0.05;(2)???w?8SSEPm????,P<0.05;(3)???w?8SEPt????,P>0.05
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?F?????;mMEPt???E(???M?m????45%),???8
mMEPt???????9???????????y?m?m???????F??
??,?%?????????????????d??????W,
4W????(???L
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[6]W????]??,?????q,?t???y?q?A???y???????????7?C???d??[]
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01