CALCIUM LACTATE
Prepared at the 18th JECFA (1974), published in NMRS 54B (1975) and in
FNP 52 (1992). Metals and arsenic specifications revised at the 59th JECFA
(2002). An ADI 'not limited' was established at the 17th JECFA (1973)
SYNONYMS INS No. 327
DEFINITION
Chemical names Calcium dilactate, calcium dilactate hydrate, 2-Hydroxypropanoic acid calcium
salt
C.A.S. number 814-80-2
Chemical formula C6H10CaO6 · xH2O (x = 0 - 5)
Structural formula
Formula weight 218.22 (anhydrous)
Assay Not less than 98.0% of on the dried basis
DESCRIPTION White to cream coloured, almost odourless, crystalline powder or granules.
The pentahydrate is somewhat efflorescent.
FUNCTIONAL USES Buffer, dough conditioner, yeast food
CHARACTERISTICS
IDENTIFICATION
Solubility (Vol. 4)
Soluble in water, practically insoluble in ethanol
Test for lactate (Vol. 4)
Passes test
Test for calcium (Vol. 4)
Passes test
PURITY
Loss on drying (Vol. 4)
Not more than 30% (120o, 4 h)
pH (Vol. 4)
6.0-8.0 (1 in 20 soln)
Acidity Dissolve 1 g of the sample in 20 ml of water, add 3 drops of phenolphthalein
TS, and titrate with 0.1 N sodium hydroxide. Not more than 0.5 ml should be
required.
Magnesium and alkali
salts
Not more than 1% mg/kg
Dissolve 1 g of the sample in 40 ml of water, add 0.5 g of ammonium chloride,
boil, and add about 20 ml of ammonium oxalate TS. Heat the solution on a
water bath for 1 h, cool, add water to 100 ml, and filter. To 50 ml of the filtrate,
add 0.5 ml of sulfuric acid, evaporate to dryness, and ignite to constant weight.
The residue should not exceed 5 mg.
Fluoride (Vol. 4)
Not more than 30 mg/kg
Lead (Vol. 4) Not more than 2 mg/kg
Determine using an atomic absorption technique appropriate to the specified
level. The selection of sample size and method of sample preparation may be
based on the principles of the method described in Volume 4, “Instrumental
Methods.”
METHOD OF
ASSAY
Dissolve about 350 mg of previously dried sample, accurately weighed, in 150
ml of water containing 2 ml of dilute hydrochloric acid TS. While stirring,
preferably with a magnetic stirrer, add about 30 ml of 0.05 M disodium
ethylenediaminetetraacetate from a 50-ml buret. Then add 15 ml of sodium
hydroxide TS and 300 mg of hydroxy-naphthol blue indicator, and continue the
titration to a blue end-point. Each ml of 0.05 M disodium
ethylenediaminetetraacetate is equivalent to 10.91 mg of C6H10CaO6.
CALCIUM LACTATE
SYNONYMS
DEFINITION
Chemical names
C.A.S. number
Chemical formula
Structural formula
Formula weight
Assay
DESCRIPTION
FUNCTIONAL USES
CHARACTERISTICS
IDENTIFICATION
PURITY
Acidity
Magnesium and alkali salts
Lead (Vol. 4)
METHOD OF ASSAY