images in clinical medicine
Th e new england journal o f medicine
n engl j med 364;8 nejm.org february 24, 2011758
A 40-year-old Korean woman who had been immobilized in bed for several weeks while recovering from tuberculous meningitis reported having pain in the right hip. Her right leg was externally rotated and flexed.
She reported discomfort on any passive movement, as well as tenderness in the
gluteal region. Plain radiographs of the pelvis were unremarkable. Computed tomog-
raphy, performed 1 month later because of ongoing pain, showed a well-defined
calcified mass within the gluteus minimus muscle on an axial view (Panel A) and
a sagittal view (Panel B), with bony trabeculation and cortex formation (arrows).
Myositis ossificans (also known as heterotopic ossification) refers to the deposition
of extraskeletal bone within soft tissue. Although the condition sometimes occurs
spontaneously, it often is the result of trauma, surgery, burns, or neurologic injury.
The calcification typically occurs within 2 to 6 weeks after injury. Early biopsy is
not recommended because of the difficulty in distinguishing the formation from
cancer. Preemptive radiotherapy in high-risk patients and surgical excision of mature
lesions are recognized therapies. The role of nonsurgical therapies is unclear. Our
patient was treated with analgesic agents and returned to Korea for ongoing care.
Copyright © 2011 Massachusetts Medical Society.
Myositis Ossificans
Deborah A. Martin, B.M., B.S.
Sanjaya Senanayake, M.B., B.S.
Canberra Hospital
Canberra, ACT, Australia
deborah.martin@act.gov.au
A B
The New England Journal of Medicine
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