阿托伐他汀钙片 阿托伐他汀钙片配合负压密闭钻孔引流治疗慢性硬膜下血肿的效果分析

阿托伐他汀钙片 阿托伐他汀钙片配合负压密闭钻孔引流治疗慢性硬膜下血肿的效果分析 龙源期刊网 阿托伐他汀钙片配合负压密闭钻孔引流治疗慢性硬膜下血肿的效果分析 作者:卢峰 林世水 魏德 来源:《中国当代医药》2016年第09期 [摘要] 目的 分析阿托伐他汀钙片配合负压密闭钻孔引流与传统钻孔引流治疗慢性硬膜下血肿(CSDH)的疗效。方法 纳入2011年1月,2014年1月因CSDH在福建省立医院神经 1 外科手术治疗患者40例，根据手术的不同将其分为研 究组与对照组。研究组进行负压密闭钻孔引流，术后规律服 用阿托伐他汀钙片治疗;对照组进行传统钻孔引流术。观察 两组患者手术前后头痛VAS评分、术前血肿量、术后血肿 量和术后颅内积气量。 结果 治疗前，两组患者头痛VAS 评分、硬膜下血肿量比较差异无统计学意义(P>0.05)。 研究组术后血肿量为(8.45?6.11)ml、颅内积气(2?1.15) ml，VAS评分(1?0.55)分;对照组术后血肿量为(19.55?7.90) ml、颅内积气(12.05?8.15)ml、VAS评分(3?0.65)分， 两组比较差异有统计学意义(P [关键词] 负压密闭钻孔;阿托伐他汀钙片;传统钻孔引流; 颅内积气;VAS评分 [中图分类号] R651.1+5 [文献标识码] A [文章编号] 1674-4721(2016)03(c)-0051-03 [Abstract] Objective To analyze the efficacy of airtight drilling drainage with negative pressure combined with atorvastatin calcium tablets in the treatment of chronic subdural hematoma. Methods 40 patients with CSDH who were operated in neurosurgical department of Fujian 2 provincial hospital from January 2011 to April 2014 were selected and divided into research group and control group based on different procedures.Research group was given the vacuum sealed drainage，postoperative treatment of regular use of atorvastatin calcium tablets，while control group was given traditional drilling drainage.Preoperative and postoperative VAS scores，hematoma volume， pneumocephalus were observed. Results Before treatment， there was no significant difference between hematoma or VAS rating in both groups(P>0.05).For research group， postoperative VAS score was (1?0.55)，the residue amount was(8.45?6.11) ml， phemocephalus was(2?1.15) ml;For control group，VAS score was(3?0.65)，the residue amount was(19.55?7.90) ml，phemocephalus was(12.05?8.15) ml，with statistical difference(P [Key words] Airtight drilling drainage with negative pressure;Atorvastatin calcium tablets;Traditional drilling and drainage;Phemocephalus;VAS score 3 慢性硬膜下血肿(chronic subdural hematoma，CSDH)是一类常见的颅内血肿，普通人群发生率约为0.05%，>70岁人群发生率为5.8%[1]。外伤是常见原因，与普通人群比较，老年人血肿复发率明显升高[2-3]。目前手术治疗是临床上治愈CSDH最为有效的一种治疗方法，而传 百度搜索“就爱阅读”,专业资料、生活学习,尽在就爱阅读网92to.com,您的在线图馆! 4