05 Summary of the revision

KHP IV summary Summary of the Revision The amendments from the Korean Herbal Pharmacopoeia Third Edition (KHP 3) are as followed: 1. The revised and notified contents after Korean Herbal Pharmacopoeia Third Edition are shown in this edition. 2. The order of the contents is the General Principles, the General Notices of the Korean Pharmacopoeia Eighth Edition, the official monographs of each drug, Poh Je Bub, the general assay methods, and the indices. 3. The monographs are indexed alphabetically. 4. Each monograph is recorded in the following order, excluding the void data: 1) name in Latin 2) name in Korean 3) definition 4) content rule 5) manufacturing 6) description 7) identification 8) purity test 9) loss on drying 10) moisture content 11) ash 12) acid insoluble ash 13) oil content 14) extract content 15) quantitative assay 16) storage 17) processing (Poh Je Bub) 18) grade 5. The identification is conducted in the following order, excluding the void data: 1) color reaction 2) precipitation reaction 3) decomposition reaction 4) ultraviolet spectrum, visible spectrum, infrared absorption spectrum 5) special reaction 6) qualitative assay of positive and negative ions 7) filter paper chromatography, thin layer chromatography 8) gas chromatography, liquid chromatography 6. The purity test is conducted in the following order, excluding the void data: 1) color, odour, taste and etc. 2) inorganic salt 3) heavy metal 4) arsenic 5) organic 6) foreign substance 7) evaporation residue 8) color product with sulfuric acid 7. Extract contents are listed in the following order, excluding the void data: 1) weak ethanol extract 2) water extract 3) ether extract 4) etc. 8. The followings are revisions, addenda, or eliminations at the General Provisions: 1) The full title in English is added as the Korean Herbal Pharmacopoeia (the article 1). 2) The clause, "However, the grade, the processing method, and the storage conditions on the official monograph are given for information, and should not be taken as indicating standard for conformity." is added (the article 4). 3) The measuring units and the term have been revised as "l, ml, l, °, weight" to "L, mL, L, °C, mass or quantity of matter," respectively, and are added to the Korean Pharmacopoeia Eighth Edition, the article 12 (the article 5). 4) The article related to extreme quantity is eliminated. 9. The revised details on the official monographs are as followed: 1) The Korean Herbal Pharmacopoeia records total of 383 official monographs: 21 new monographs and 21 eliminations from KHP 3 that has total of 384 official monographs. 2) The additional monographs are as followed (20 monographs): ALOE, AUCKLANDIAE RADIX, AURANTII PERICARPIUM, BULBUS FRITILLARIAE CIRRHOSAE, CANTHARIDES, CATALPAE FRUCTUS, CINCHONAE CORTEX, CRASSIRHIZOMAE RHIZOMA, DATURAE FOLIUM, DIGENEA, DIPSACI RADIX, ERGOTA PREPARATA, FEL URSI, GINSENG RADIX PALVA, GRANATI CORTEX, MOSCHUS, RAUWOLFIA RADIX, RHEI UNDULATAI RHIZOMA, SCOPOLIAE FOLIUM, STROPHANTHI SEMEN 3) The eliminated monographs are as followed (21 monographs): AMOMI ROTUNDUS FRUCTUS, ANGELICAE KOREANAE RADIX, ANGELICAE PUBESCENTIS RADIX, ARISAEMATIS RHIZOMA, ASPARAGI RADIX, DEPOSITUM URINAE PRAEPARATUM, EPIMEDII HERBA, FRITILLARIAE BULBUS, GASTRODIAE RHIZOMA, GINKGONIS FOLIUM, LONGAN ARILLUS, LONICERAE FLOS, NELUMBINIS SEMEN, PAEONIAE RADIX RUBRA, POGSTEMI HERBA, POLYGONATI RHIZOMA, REHMANNIAE RADIX, SALVIAE MILTIORRHIZAE RADIX, SCROPHULARIAE RADIX, TRICHOSANTHIS SEMEN, VISCI HERBA 4) The monographs with the revised name are as followed: [KHP 3 in 1987] ALLI BULBUS ANTHRISI RADIX AQUILLARIAE LIGNUM ARTEMISIAE ASIATICAE HERB AURANTII FRUCTUS AURANTII IMMATURI PERICARPIUM BIOTAE ORIENTALIS FOLIUM BUDDLEIAE FLOS CHRYSANTHEMI SIBIRICI HERBA CYNANCHI WILFORDI RADIX DRACONIS SORGUIS FULVIS FUMI CARBONISATUS GINKGO SEMEN LORANTHI RAMULUS LYCOPDIUM LYSIMACHIAE FOENUM-GRAECUMI HERBA MELONIS CARYX MUCUNAE CAULIS NOTARCHI EACHII OVUM PASORALIAE SEMEN PERILLAE SEMEN PHLOMIS RADIX PINII KORAIENSIS SEMEN PTEROPI FAECES REMOTIFLORAE RADIX RESINA POPULII ROSEAE FRUCTUS SAUSSUREAE RADIX TORILIDIS FRUCTUS TRITICI IMMATRI SEMEN [KHP 4 in 2002] ALLII BULBUS ANGELICAE DECURSIVAE RADIX AQUILARIAE LIGNUM ARTEMISIAE ARGYI HERB AURANTII FRUCTUS IMMATURUS CITRII UNSHIU IMMATURI PERICARPIUM THUJAE ORIENTALIS FOLIUM BUDDLEJAE FLOS CHRYSANTHEMI ZAWADSKII HERBA CYNANCHI WILFORDII RADIX DRACONIS SANGUIS PULVIS FUMI CARBONISATUS GINKGONIS SEMEN VISCI HERBA ET LORANTHI RAMULUS LYCOPODIUM LYSIMACHIAE FOENUM-GRAECI HERBA MELONIS PEDICELLUS SPATHOLOBI CAULIS NOTARCHI LEACHII OVUM PSORALEAE SEMEN PERILLAE JAPONICAE SEMEN PHLOMIDIS RADIX PINI KORAIENSIS SEMEN TROGOPTERORUM FAECES REMOTIFLORI RADIX RESINA POPULI ROSAE FRUCTUS AUCKLANDIAE RADIX CNIDI FRUCTUS TRITICI LEVIS SEMEN 5) Name in Latin: (1) The monographs revised on that category are as followed (11 monographs): ASTERIS RADIX, BAMBUSAE CONCRETIO SILICEA, BELAMCANDAE RHIZOMA, HOLOTRICHIA, JUGLANDIS SEMEN, LITCHI SEMEN, LUMBRICUS, PERILLAE SEMEN, RESINA POPULI, TESTUDINIS PLASTRUM, UNCARIAE RAMULUS ET UNCUS (2) The monographs eliminated on that category are as followed (14 monographs): ACONITI TUBER, ACORI GRAMINERI RHIZOMA, ADENOPHORAE RADIX, BISTORTAE RHIZOMA, BLETILLAE RHIZOMA, COCCULI RADIX, CYNANCHI WILFORDII RADIX, DOLICHORIS SEMEN, ERIOCAULI HERBA, GENTIANAE MACROPHYLLAE RADIX, GLECHOMAE HERBA, LAMINARIAE JAPONICAE THALLUS, OTARIAE TESTI ET PENIS, PEUCEDANI RADIX 6) The monographs revised on the Definition category are as followed (212 monographs): ACONITI CILIARE TUBER, ACONITI TUBER, ACTINIDIAE FRUCTUS, ADENOPHORAE RADIX, AGASTACHIS HERBA, AGKISTRODON, AGRIMONIAE HERBA, AKEBIAE FRUCTUS, ALLII MACROSTEMI BULBUS, ALOE, ALPINIAE KATSUMADAII SEMEN, ALPINIAE OFFICINARI RHIZOMA, AMOMI TSAO-KO FRUCTUS, ANETHI FRUCTUS, ANGELICAE DECURSIVAE RADIX, ANGELICAE TENUISSIMAE RADIX, ANTELOPIS CORNU, AQUILARIAE LIGNUM, ARCAE CONCHA, ARECAE PERICARPIUM, ARISTOLOCHIAE FRUCTUS, ARISTOLOCHIAE RADIX, ARTEMISIAE ARGYI HERB, ASTRAGALI SEMEN, AUCKLANDIAE RADIX, AURANTII FRUCTUS IMMATURUS, AURANTII PERICARPIUM, BAMBUSAE CONCRETIO SILICEA, BENINCASAE PERICARPIUM, BENINCASAE SEMEN, BETULAE CORTEX, BOMBYCIS EXCREMENTUM, BOMEOLUM, BUDDLEJAE FLOS, BUFO, BULBUS FRITILLARIAE CIRRHOSAE, CAESALPINIAE LIGNUM, CALAMINA, CANTHARIDES, CARAGANAE RADIX, CASSIAE CORTEX INTERIOR, CELOSIAE SEMEN, CERVI CORNU, CERVI PARVUM CORNU, CHRYSANTHEMI FLOS, CHRYSANTHEMI ZAWADSKII HERBA, CIBOTII RHIZOMA, CICADIDAE PERIOSTRACUM, CINNAMOMI CORTEX SPISSUS, CINNAMOMI RAMULUS, CIRSII HERBA, CISTANCHIS HERBA, CITRI UNSHIU SEMEN, CITRII UNSHIU IMMATURI PERICARPIUM, CLADONIAE HERBA, CLEMATIDIS RADIX, CNIDI FRUCTUS, COCCULI RADIX, CODONOPSIS PILOSULAE RADIX, CORIANDRI FRUCTUS, CREMASTRAE TUBER, CRASSIRHIZOMAE RHIZOMA, CUBEBAE FRUCTUS, CURCULIGINIS RHIZOMA, CURCUMAE LONGAE RHIZOMA, CUSCUTAE SEMEN, CYMBOPOGONIS HERBA, CYNANCHI RADIX, CYNANCHI STAUNTONII RHIZOMA, CYNOMORII HERBA, DALBERGIAE ODORIFERAE LIGNUM, DENDROBII HERBA, DIANTHI HERBA, DICHROAE RADIX, DICTAMNI RADICIS CORTEX, DIPSACI RADIX, DOLICHORIS SEMEN, DRABAE SEMEN, DRACONIS SANGUIS, DRYNARIAE RHIZOMA, ECHINOPSIS RADIX, ELSHOLTZIAE HERBA, EQUISETI HERBA, ERETMOCHELYDIS CARAPAX, ERIOCAULI HERBA, ERYCIBAE CAULIS, EUMECES, EUONYMI LIGNUM SUBERALATUM, EUPHORBIAE KANSUI RADIX, EUPHORBIAE LATHYRIDIS SEMEN, EUPOLYPHAGA, EURYALES SEMEN, FARFARAE FLOS, FEL TAURI, FEL URSI, FERULAE RESINA, FOSSILIA SPIRIFERIS, FRAXINI CORTEX, GANODERMA, GASTRODIAE HERBA, GECKO, GLECHOMAE HERBA, GOSSYPII SEMEN, GUTTI, HALIOTIDIS CONCHA, HEMEROCALLIDIS RADIX, HIRUDO, HOELEN CUM RADIX, HOLOTRICHIA, HORDEI FRUCTUS GERMINATUS, HOVENIAE SEMEN CUM FRUCTUS, HUMULI HERBA, HYDNOCARPI SEMEN, INDIGO PULVERATA LEVIS, LASHIOSPHAERA, LIGUSTRI FRUCTUS, LILII BULBUS, LINDERAE RADIX, LITCHI SEMEN, LONICERAE FOLIUM, LOPHATHERI HERBA, LUMBRICUS, LYCOPI HERBA, LYSIMACHIAE FOENUM-GRAECI HERBA, MAGNOLIAE FLOS, MANITIS SQUAMA, MANTIDIS OOTHECA, MARGARITUM, MARSDENIAE LONGIPI HERBA, MAYDIS STIGMA, MELANDRII HERBA, MELONIS PEDICELLUS, MOMORDICAE SEMEN, MORI FOLIUM, MORI FRUCTUS, MORI RAMULUS, MORINDAE RADIX, MUME FRUCTUS, NARDOSTACHYOS RHIZOMA, NELUMBINIS RHIZOMATIS NODUS, NOTOGINSENG RADIX, NUPHARIS RHIZOMA, OLIBANUM, OMPHALIA, OROBANCHIS HERBA, OROSTACHYS HERBA, ORYZAE RADIX, OTARIAE TESTI ET PENIS, PERILLAE SEMEN, PEUCEDANI RADIX, PHASEOLI ANGULARIS SEMEN, PHLOMIDIS RADIX, PHRAGMITIS RHIZOMA, PHYTOLACCA RADIX, PINI POLLEN, PIPERIS LONGI FRUCTUS, PISCIS COLLA, POLYGONATI ODORATI RHIZOMA, POLYGONI CUSPIDATI RADIX, PRUNI NAKAII SEMEN, PSORALEAE SEMEN, PUERARIAE FLOS, PULSATILLAE RADIX, PULVIS ACONITI TUBERIS PURIFICATUM, PYROLAE HERBA, PYRROSIAE FOLIUM, QUISQUALIS FRUCTUS, RAPHANI SEMEN, RAUWOLFIA RADIX, REHMANNIAE RADIX CRUDUS, REMOTIFLORI RADIX, RESINA POPULI, RHEI UNDULATAI RHIZOMA, RICINI SEMEN, ROSAE LAEVIGATAE FRUCTUS, RUBIAE RADIX, RUMECIS RADIX, SANGUISORBAE RADIX, SANTALI ALBI LIGNUM, SANTALINI LIGNUM RUBRUM, SARGASSUM, SCIRPI RHIZOMA, SEDI HERBA, SEPIAE OS, SERPENTIS FEL, SERPENTIS PERIOSTRACUM, SIEGESBECKIA HERBA, SPATHOLOBI CAULIS, STEMONAE RADIX, STERCULIAE SCAPHIGERAE SEMEN, STICHOPUS, STYRAX LIQUIDES, TABANUS, TAMARICIS RAMULUS, TARAXACI HERBA, TERMINALIAE FRUCTUS, TESTUDINIS PLASTRUM, THUJAE ORIENTALIS FOLIUM, THYMI HERBA, TRACHELOSPERMI CAULIS, TRACHYCARPI PETIOLUS, TRIGONELLAE SEMEN, TROGOPTERORUM FAECES, TYPHAE POLLEN, ULMI PASTA SEMEN, UNCARIAE RAMULUS ET UNCUS, VERATRI RHIZOMA, VERONICASTRI RHIZOMA, VESPAE NIDUS, VESPERTILII EXCREMENTUM, VIOLAE HERBA, VISCI HERBA ET LORANTHI RAMULUS 7) The monographs revised on the Description category are as followed (7 monographs): AQUILARIAE LIGNUM, ARTEMISIAE ARGYI HERB, AURANTII FRUCTUS IMMATURUS, CERVI PARVUM CORNU, CHRYSANTHEMI FLOS, CURCULIGINIS RHIZOMA, SCIRPI RHIZOMA 8) The monographs revised on the Identity test category are as followed (34 monographs): ACONITI KOREANI TUBER, ALOE, ASTRAGALI SEMEN, AURANTII PERICARPIUM, BLETILLAE RHIZOMA, BOMEOLUM, BUDDLEJAE FLOS, CASSIAE CORTEX INTERIOR, CEPHALONOPLOSI HERBA, CERVI PARVUM CORNU, CHAENOMELIS FRUCTUS, CHRYSANTHEMI ZAWADSKII HERBA, CINNABARIS, CINNAMOMI CORTEX SPISSUS, CINNAMOMI RAMULUS, CLEMATIDIS RADIX, CRASSIRHIZOMAE RHIZOMA, DALBERGIAE ODORIFERAE LIGNUM, EUPHORBIAE PEKINENSIS RADIX, FEL TAURI, FERULAE RESINA, HAEMATITUM, LITHARGYRUM, MOSCHUS, OMPHALIA, RHEI UNDULATAI RHIZOMA, RUBI FRUCTUS, SOPHORAE SUBPROSTRATAE RADIX, STRYCHNI IGNATII SEMEN, SUILUS FEL, SULFUR, TYPHAE POLLEN, VESPERTILII EXCREMENTUM, ZINGIBERIS RHIZOMA CRUDUS 9) Purity test: (1) The monographs eliminated on that category are as followed (2 monographs): FEL URSI, RHEI UNDULATAI RHIZOMA (2) The monographs revised on that category are as followed (4 monographs): CALOMELAS, MOSCHUS, SACCHARUM GRANORUM, SULFUR 10) The monographs revised on the Loss on drying category are as followed (22 monographs): ACONITI TUBER, AGASTACHIS HERBA, ANGELICAE DECURSIVAE RADIX, AQUILARIAE LIGNUM, ARECAE PERICARPIUM, ARTEMISIAE ARGYI HERB, ASTERIS RADIX, CHAENOMELIS FRUCTUS, CHRYSANTHEMI FLOS, CISTANCHIS HERBA, CITRII UNSHIU IMMATURI PERICARPIUM, CLEMATIDIS RADIX, CNIDI FRUCTUS, GINKGONIS SEMEN, LINDERAE RADIX, OLIBANUM, POLYGONI MULTIFLORI RADIX, RAPHANI SEMEN, SANGUISORBAE RADIX, ULMI CORTEX, UNCARIAE RAMULUS ET UNCUS, ZINGIBERIS RHIZOMA CRUDUS 11) The monographs revised on the Total Ash category are as followed (46 monographs): ACONITI CILIARE TUBER, ACONITI TUBER, ACORI GRAMINERI RHIZOMA, ADENOPHORAE RADIX, AGASTACHIS HERBA, ALPINIAE OFFICINARI RHIZOMA, ANGELICAE DECURSIVAE RADIX, ARCTII SEMEN, ARECAE PERICARPIUM, ARTEMISIAE ARGYI HERB, ASTERIS RADIX, BOMBYCIS CORPUS, CHAENOMELIS FRUCTUS, CHRYSANTHEMI FLOS, CINNAMOMI CORTEX SPISSUS, CINNAMOMI RAMULUS, CISTANCHIS HERBA, CITRII UNSHIU IMMATURI PERICARPIUM, CLEMATIDIS RADIX, CNIDI FRUCTUS, CODONOPSIS PILOSULAE RADIX, CURCUMAE LONGAE RHIZOMA, CUSCUTAE SEMEN, DOLICHORIS SEMEN, EURYALES SEMEN, KALOPANACIS CORTEX, KOCHIAE FRUCTUS, LIGUSTRI FRUCTUS, LILII BULBUS, LINDERAE RADIX, LONICERAE FOLIUM, LYCII RADICIS CORTEX, MAGNOLIAE FLOS, MORINDAE RADIX, OLIBANUM, PERILLAE SEMEN, POLYGONI MULTIFLORI RADIX, PRUNI NAKAII SEMEN, PSORALEAE SEMEN, RAPHANI SEMEN, SANGUISORBAE RADIX, SCIRPI RHIZOMA, SMILACIS RHIZOMA, TRIBULI FRUCTUS, VITICIS FRUCTUS, ZINGIBERIS RHIZOMA CRUDUS 12) Acid insoluble ash: (1) The monographs added on that category are as followed (1 monograph): LONICERAE FOLIUM (2) The monographs revised on that category are as followed (21 monographs): ACONITI TUBER, ACORI GRAMINERI RHIZOMA, ADENOPHORAE RADIX, AGASTACHIS HERBA, ALPINIAE OFFICINARI RHIZOMA, ANGELICAE DECURSIVAE RADIX, ARCTII SEMEN, ARTEMISIAE ARGYI HERB, ASTERIS RADIX, CHRYSANTHEMI FLOS, CISTANCHIS HERBA, CLEMATIDIS RADIX, CNIDI FRUCTUS, CODONOPSIS PILOSULAE RADIX, DOLICHORIS SEMEN, KOCHIAE FRUCTUS, PERILLAE SEMEN, PSORALEAE SEMEN, SCIRPI RHIZOMA, TRIBULI FRUCTUS, VITICIS FRUCTUS (3) The monographs eliminated on that category are as followed (4 monographs): CERVI PARVUM CORNU, CHAENOMELIS FRUCTUS, KALOPANACIS CORTEX, LIGUSTRI FRUCTUS 13) Oil content: (1) The monographs revised on that category are as followed (7 monographs): AGASTACHIS HERBA, ALPINIAE OFFICINARI RHIZOMA, ANGELICAE DECURSIVAE RADIX, ARTEMISIAE ARGYI HERB, CINNAMOMI RAMULUS, CITRII UNSHIU IMMATURI PERICARPIUM, VITICIS FRUCTUS (2) The monographs eliminated on that category are as followed (3 monographs): CHRYSANTHEMI FLOS, PERILLAE SEMEN, PSORALEAE SEMEN 14) Extract content: (1) The monographs revised on that category are as followed (34 monographs): AGASTACHIS HERBA, ALPINIAE OFFICINARI RHIZOMA, ANGELICAE DECURSIVAE RADIX, AQUILARIAE LIGNUM, ARCTII SEMEN, ARECAE PERICARPIUM, ARTEMISIAE ARGYI HERB, ASTERIS RADIX, CHAENOMELIS FRUCTUS, CHRYSANTHEMI FLOS, CINNAMOMI RAMULUS, CISTANCHIS HERBA, CITRII UNSHIU IMMATURI PERICARPIUM, CLEMATIDIS RADIX, CNIDI FRUCTUS, CODONOPSIS PILOSULAE RADIX, CUSCUTAE SEMEN, CYNOMORII HERBA, KAKI CALYX, KALOPANACIS CORTEX, KOCHIAE FRUCTUS, LIGUSTRI FRUCTUS, LINDERAE RADIX, LYCII RADICIS CORTEX, MORINDAE RADIX, OLIBANUM, POLYGONI MULTIFLORI RADIX, PRUNI NAKAII SEMEN, PSORALEAE SEMEN, RAPHANI SEMEN, SANGUISORBAE RADIX, SCIRPI RHIZOMA, UNCARIAE RAMULUS ET UNCUS, VITICIS FRUCTUS (2) The monographs eliminated on that category are as followed (3 monographs): EURYALES SEMEN, PERILLAE SEMEN, TYPHAE POLLEN 15) Quantitative Assay: (1) The monographs revised on that category are as followed (11 monographs): ALUMEN, GRANATI CORTEX, HYDRARGYRUM, LITHARGYRUM, MINIUM, PULVIS ACONITI TUBERIS PURIFICATUM, RAUWOLFIA RADIX, REALGAR, SACCHARUM GRANORUM, STRYCHNI IGNATII SEMEN, VERMILIONUM (2) The monographs eliminated on that category are as followed (3 monographs): ACONITI CILIARE TUBER, ACONITI KOREANI TUBER, ACONITI TUBER