Dominant and Recessive Genes：显性基因和隐性基因

Dominant and Recessive Genes：显性基因和隐性基因 Section Animal Science Unit Unit 6: Reproduction and Genetics Lesson Title Lesson 12: Dominant and Recessive Genes Student Learning Objectives (Enablers) As a result of this lesson, the student will … 1. Understand the six fundamental types of mating. 2. Be able to perform punnett squares for one and two pair of contrasting traits. 3. Be able to calculate phenotypic and genotypic ratios. Time: Instruction time for this lesson: 50 minutes. Resources/References , Scientific Farm Animal Production , Biology: “Principles and Explorations” Tools, Equipment, and Supplies , Unit 4, Lesson 12 Recessive and Dominant Genes Overheads or PowerPoint , Worksheet 1 (one per student) worksheets are found at the end of power point , Worksheet 2 (one per student) , Worksheet 3 (one per student) , Unit 4, Lesson 12 Dominant and Recessive Genes Assessment (one per student) Key Terms. The following terms are presented in this lesson and appear in bold italics: Homozygous Dominant Homozygous Recessive Heterozygous Phenotype Genotype Punnett Square Phenotypic Ratio Genotypic Ratio Unit 4, Lesson 12: Dominant and Recessive Genes 1 Interest Approach Display overhead number one. (Unit 4, Lesson 12 Dominant and Recessive Genes PP 1) I want each of you to take the next thirty seconds to investigate the tops of your hands. Look for scars, wrinkles, hair, and veins. Your time starts now. Raise your hand if you have hair above your knuckles. Good, thank you. Based on what you have learned from the previous lessons we know that the presence of hair above the knuckles is caused by a dominant allele, H. Those of you who have no hair above your knuckles, what is your genotype for this trait? (hh is the only possibility) Under what circumstances could a parent without hair above their knuckles produce a child with hair above their knuckles? (The second parent must have hair above their knuckles) Great job class. Today we are going to explore how traits are passed from generation to generation. We will discover the mystery that bewildered the world for so many centuries. Have you ever been with someone and met one of his or her relatives that you had never met before. You know, before you are even introduced, that they are related. How do these family similarities remain so strong throughout generation after generation? If you have any doubt ask one of your grandparents to see pictures of their parents, and themselves when they were children. I am willing to bet that you will find striking similarities. Today we will invest our time exploring the fascinating science of genetics. Unit 4, Lesson 12: Dominant and Recessive Genes 2 Summary of Content and Teaching Strategies Objective 1. Understand the six fundamental types of mating. Objective 2. Be able to perform punnett squares for one and two pair of contrasting traits. Objective 3. Be able to calculate phenotypic and genotypic ratios. As a review from the previous lesson, ask students to define the three types of gene combinations, homozygous dominant, homozygous recessive and heterozygous. Show the first half of overhead number one (Point A and sub-points 1-3). Through this discussion you should lead students to the Red Angus breed. For the purpose of this lesson B is the dominant gene in cattle that codes for a black coat; b is the recessive form of this allele that codes for a red coat. Using just this information can you think of a breeding program where the recessive gene was used to develop an entirely new breed of beef cattle? Very good, Red Angus is an example of how a breeding program successfully isolated a recessive gene and through careful management used that gene to found a new breed. When I say genetics, I want you to use the next minute to write down six possible combinations that could result from the breeding of the three types of individuals displayed in the overhead, BB, Bb, and bb. What can I clarify? Genetics. After the minute has expired use the white board to write down what they came up with. Once you have all six, display the rest of overhead two. This next portion will use overheads three through eight in conjunction with a Little Professor Moment. When I say little professor I would like each of you to find a partner. Keep in mind that you need to be in pairs with an area large enough for both of your notebooks. Little Professor. Good job guys. I now need one person in each group to raise your hand. Those of you with your hands up will be Little Professor I and your partners will be Little Professor II. Little Professor II’s. For the next couple of minutes you are not to listen to me. You may read, daydream, or put your head down. The only thing you can’t do is leave your seats, talk, or be a disruption. Display the left half of slide number three. (Unit 4, Lesson 12 Dominant and Recessive Genes PP 3) Little Professor I’s, the information on the overhead is what you, as masters in your field, will teach your partners. When two homozygous dominant individuals are mated, each can produce only one kind of gamete. In our particular example, this gamete can only Unit 4, Lesson 12: Dominant and Recessive Genes 3 carry gene B. The union of gametes from two homozygous dominant parents results in a zygote that is homozygous dominant. In other words, the only possible combination is B x B = BB. Thus, homozygous parents produce only homozygous dominant offspring. Display the right half of overhead three but instruct them that they don’t need that information in their notes at this time. (Unit 4, Lesson 12 Dominant and Recessive Genes PP 3) Little Professor I’s, you have the next thirty seconds to instruct your partners on this information, be sure they get the most important information into their notebooks. Little Professor I’s, it is now your turn to take a break me while I talk with the Little Professor II’s. Display overhead number four, but instruct them not to take notes on the right-hand table. (Unit 4, Lesson 12 Dominant and Recessive Genes PP 4) Little professor II’s, the mating of a homozygous dominate with a heterozygous individual results in an expected ratio of one homozygotes dominant to one heterzygote. parent produces only one kind of gamete, a dominant B. The The homozygous dominant heterozygous parent produces in equal proportion two kinds of gametes, one carrying the dominant gene (B) and one carrying the recessive gene (b). The chance are equal that a gamete from the parent producing only the one kind of gamete will unite with each of the two kinds of gametes produced by the heterozygous parent; therefore, the number of homozygous dominant offspring and heterozygous offspring produced should be approximately equal. Little Professor II’s, take the next thirty seconds, as the experts in your field, to instruct your partners. Little Professor I’s, it’s your turn to listen to me, Little Professor II’s you know the routine. Display overhead number five. (Unit 4, Lesson 12 Dominant and Recessive Genes PP 5) Little Professor I’s, the homozygous dominant individual can produce only gametes carrying the dominant gene. The recessive individual must be homozygous recessive to express the recessive trait. Therefore, the individual produces only gametes carrying the recessive gene. When the two types of gametes unite, all offspring produced receive both the dominant and the recessive gene and are thus all heterozygous. Little Professor I’s take the next thirty seconds to teach your partners. Little Professor II’s you are back with me and Little Professor I’s it is your turn to relax. Display overhead number six. (Unit 4, Lesson 12 Dominant and Recessive Genes PP 6) Unit 4, Lesson 12: Dominant and Recessive Genes 4 Each of the two heterozygous parents produces two kinds of gametes in approximately equal ratios. One kind of gamete carries the dominant gene and the other kind carries the recessive gene. The two kinds of gametes produced by one parent each have an equal chance of uniting with each of the two types of gametes produced by the other parent. Thus, four equal chance unions of gametes are possible. If the gamete carrying the dominant gene from on parent unites with the gamete carrying the dominant gene from the other parent, the offspring produced are homozygous dominant. If the gamete carrying the dominant gene from one parent unites with the gamete carrying the recessive gene form the other parent, the offspring are heterozygous. The latter combination of genes can occur in two ways, the dominant gene can come from male parent and the recessive gene from the female parent, or the dominant gene can come from the female parent and the recessive gene form the male parent. When the gametes carrying the recessive gene from both parents unite the offspring produced will be homozygous recessive. The total expected ratio among the offspring of two heterozygous parents is one homozygous dominant to two heterozygous to one homozygous recessive. This 1:2:1 is the genotypic ratio. The appearance of the offspring is in the ratio of three dominant to one recessive because the homozygous dominant and the heterozygous animals are all black and cannot be genetically distinguished from one another visually. This 3:1 ratio, based on external appearance is called the phenotypic ratio. Little Professor II’s, take the next minute to teach your partners this new information. Very good job! Little Professor II’s take some well-deserved time off, Professor I's your back with me. Display overhead number seven. (Unit 4, Lesson 12 Dominant and Recessive Genes PP 7) Little Professor I’s, the heterozygous individual produces two kinds of gametes, one carrying the dominant gene and the other carrying the recessive gene, in approximately equal numbers. The recessive individual produces only the gametes carrying the recessive gene. There is an equal chance that the two kinds of gametes produced by the heterozygous parent will unite with the one kind of gamete produced by the homozygous recessive parent. The offspring produced when these gametes unite thus occur in an expected ratio of three heterozygous to one homozygous recessive. Little professors’, take the next thirty seconds to teach your partners this new information. One last time Little Professor II’s please come back to me. Little prof’s I take the next couple of minutes to relax. Display overhead number eight. (Unit 4, Lesson 12 Dominant and Recessive Genes PP 8) The recessive individuals are homozygous; therefore, they can produce gametes carrying only the recessive gene. When the gametes unite, all offspring produced will be recessive. This example illustrates the principle that recessives, when mated together, breed true. Take the next thirty seconds to instruct your partners on this information. Unit 4, Lesson 12: Dominant and Recessive Genes 5 Once they have finished, distribute worksheet number one and two to each student and allow them three minutes to complete the punnett squares. Knowledge of the combinations resulting from each of the six fundamental types of matings provides a background for understanding complex crosses. When more than one pair of genes is considered in a mating, one can understand the expected results. One can combine each of the combinations of one pair of genes with each of the other combinations of one pair of genes to obtain the expected ratio. Pass out worksheet three and display overhead nine. (Unit 4, Lesson 12 Dominant and Recessive Genes PP 9) In your little professor pairs I would like each of you to look at the information presented in the current overhead. Just like in the past six examples, B is dominant and black, b is recessive and red. In addition I have added a second trait. P is dominant for polled and p is recessive for horned. You are starting a new SAE, the bull you have bought has a genotype of BbPp and you plan to breed him to the heifer you just bought. Her genotype is also heterozygous for both traits. Take the next five minutes, working with your partner to complete worksheet three. I also ask you to figure out the genotypic and phenotypic ratio for this cross. Good luck, begin. After five minutes display overheads ten and eleven so that each student has correct information in their notes. (Unit 4, Lesson 12 Dominant and Recessive Genes PP 10, 11) Review/Summary. We have accomplished a lot today. We have discovered the six possible combinations when any two individuals are mated for the expression of traits. We completed punnett squares for each of the six types of mating exhibiting in a trait controlled by a single gene. Additionally, we worked on a more complex problem, completing a punnett square on two traits. And finally, we calculated phenotypic and genotypic ratios. Are their any questions of the information covered today? I would like you to take the remaining time to work with your partner to ensure that each of you have a complete understanding if the material as well as a complete set of notes. Unit 4, Lesson 12: Dominant and Recessive Genes 6 Application Extended classroom activity: Do an internet search on traits that can be found in livestock or humans. Do punnett squares on these traits and discuss the probabilities of the expression of these traits. SAE activity: Have students look at their current SAE’s. What traits are displayed regularly and which ones only show up less seldom. Have students research these traits to discover the dominant and recessive allele relationship in their expression. Evaluation Unit 4, Lesson 12 Dominant and Recessive Genes Worksheets 1, 2, 3 Unit 4, Lesson 12: Dominant and Recessive Genes 7