高度近视黄斑病变的OCT和FFA形态学

高度近视黄斑病变的OCT和FFA形态学 Tel:029鄄82245172摇82210956摇摇Email:IJO.2000@163.com IntEyeSci,Vol.14,No.3,Mar.2014摇摇www.ies.net.cn ·临床论著· 高度近视黄斑病变的OCT和FFA形态学分类的对比 吴彩云,张文芳,陶摇明,张摇婧,周摇然 作者单位:(730030)中国甘肃省兰州市,兰州大学第二医院眼科作者简介:吴彩云,兰州大学第二临床医学院在读硕士研究生,研究方向:眼底病学。 通讯作者:张文芳,女,主任医师,甘肃省眼科临床医学中心主(67郾80%)thaninthelacquercrack(18.64%)andVtype(13.56%),thedifferencewasstatisticallysignificant(P<0.05).ThemacularatrophytypeallbelongtotheOCTtype3.OCTtype1showedtheleastdioptreandAL,任163.,副教授,硕士研究生导师,研究方向:眼底病学.zhwenf888@收稿日期com :2013-11-11摇摇修回日期:2014-02-10 ContrastiveofmyopicOCTanalysisbetweenthefeaturesmaculopathy andFFAinhighCai-ZhangYun,RanWuZhou ,Wen-FangZhang,MingTao,JingDepartmentLanzhouofOphthalmology,LanzhouUniversitySecondCorrespondence730030,LanzhouProvince,UniversitytoGansu:Wen-FangProvince,Hospital,SecondHospital,Zhang.China DepartmentLanzhouof730030,Ophthalmology,GansuReceived:2013-11-11摇China.zhwenf888@摇Accepted:2014-02-10 163.com Abstract 誗 classificationAIM:Toassessthemorphologicalfeatures,featuresfundusmyopicfluoresceinofoptical,andmaculopathy. angiographycoherencecontrastivetomographyanalysisbetweenthe(FFA)inclinically(OCT)highand誗highMETHODS:Totally61patients(101eyes)withclinicallythroughmyopicoptometryEStandardmaculopathy.visualtodetermineLogarithmDistantvisionwasexaminedthedioptreEyesightandTable.bestIntegratedobtainedacuityperformedthrough(BCVAIOL).Axial-Master.lengthcorrectedFundus(AL)measurementsdilation.ofOCTinandpatientsFFAwerewithdonehighseparatelymyopiaexaminationsinaftereachpupilcaseindocyaninemyopicmaculopathyonthesameday.FFAandneedgreenangiogrsphy(FFA&ICGA)wasdoneiftypesbe.dioptrewereThecorrelationbetweenFFAtypesandOCTevaluated. ,BCVAanalyzed,ALand,andcentraltheirfovealassociationsthicknesswerewith誗higherRESULTSneovascularizationinthe:OCTTheprevalencetypeoflacquercracktypewas((V1)(57type.14and%)thaninthechoroidalstatistically21.43%)ofmacularatrophytypemacularatrophysignificantfluoresceintype(angiography,thedifferencewaswasP<0higher.05).inThetheprevalenceOCTtypeof2 converselythehighestcentralfovealthicknessand/orBCVA(P<0.05).TherewasnoobviousdifferencebetweenlacquercracktypeandVtypeondiopterandAL,butlacquercracktypeshowedbetterBCVAandfovealthicknesstypeand(VP<0.type05).wereThedioptersignificantlyandALloweroflacquerthanthatcrackofmacularatrophytype,whileBCVAwashigher(P<0.05).誗betweenCONCLUSIONthefeatures:ThereofwasOCTasignificantandFFAcorrelationinhighmyopicmaculopathy.TheanalysisofclinicallyhighmyopicmaculopathybasedoncombinationofOCTandFFAcanprovideinformationthatmaybeusefultomakesurethenatureofhighmyopia,disclosethepathogenesisandtooptimizepathologicmyopia:highthetreatment;myopicforeachtype. 誗KEYWORDSopticalmaculopathycoherence;hightomographymyopia;;fundusfluoresceinangiography Citationbetween:WuCY,ZhangWF,TaoGuojiYankethefeaturesZazhi(IntofEyeOCTSciand)2014;14(3):441-446 FFAM,inethighal.myopicContrastivemaculopathy.analysis 摘要 目的:探讨高度近视黄斑病变的光学相干断层扫描(OCT)和眼底荧光血管造影(FFA)的形态学特征、分类和对比分析。 :对入选的高度近视黄斑病变患者61例101眼均行对数视力检查(BCVA),一天内行散瞳眼底检查并用IOL-Master,验光确定屈光度及最佳矫正视力、OCT测量眼轴长度及FFA检查。,入选者需在同必要时行眼底联合造影(FFA&ICGA)。分析不同类型的OCT及FFA形态学特征之间的相互联系,并探讨其与屈光度、最佳矫正视力、眼轴长度及中心凹厚度之间的关系。 结果:FFA分类的漆样裂纹型在OCT分类的1型中所占比例为(21郾57.14%,显著高于新生血管型和黄斑萎缩型斑萎缩型在43%),差异有统计学意义OCT分类的2型中所占的比例为(P<0.05)。FFA67.分类的黄80%,显著高于漆样裂纹型(18.64%)和新生血管型(13.56%),差异有统计学意义(P<0.05)。OCT3型均属于FFA分类的黄斑萎缩型。OCT1型的屈光度、眼轴长度明显低于2型和3型,而最佳矫正视力和中心凹厚度则明显高于2型和3型。FFA的漆样裂纹型与新生血管型在屈光度及眼轴长度上虽无明显差异,但后者的BCVA及中心凹厚度显 441