前列腺素E受体蛋白4抗体

前列腺素E受体蛋白4抗体 英文名称 Anti-EP4/Prostaglandin E Receptor EP4 中文名称 前列腺素E受体蛋白4抗体 别 名 EP 4; EP4; EP-4; EP4R; MGC126583; PE2R4_HUMAN; PGE receptor EP4 subtype; PGE2 receptor EP4 subtype; Prostaglandin E receptor 4; Prostaglandin E receptor 4 subtype EP4; Prostaglandin E2 receptor; Prostaglandin E2 receptor EP4 subtype; Prostanoid EP4 receptor; PTGER 2; PTGER 4; PTGER2; PTGER4. 浓 度 1mg/1ml 规 格 0.1ml/100μg 0.2ml/200μg 抗体来源 Rabbit 克隆类型 polyclonal 交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, Sheep 产品类型 一抗 研究领域 信号转导 G蛋白偶联受体 蛋白分子量 predicted molecular weight: 53kDa 性 状 Lyophilized or Liquid 免 疫 原 KLH conjugated synthetic peptide derived from human EP4R/Prostaglandin E Receptor EP4 亚 型 IgG 纯化方法 affinity purified by Protein A 储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 保存条件 Store at -20 ?C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20?C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ? C. Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 产品介绍 Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. Function : Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. Subunit : Interacts with FEM1A. Subcellular Location : Cell membrane. Tissue Specificity : High in intestine and in peripheral blood mononuclear cells; low in lung, kidney, thymus, uterus, vasculature and brain. Not found in liver, heart, retina oe skeletal muscle. Post-translational modifications : Phosphorylation mediates agonist-mediated desensitization by promoting cytoplasmic retention. Similarity : Belongs to the G-protein coupled receptor 1 family. Database links : UniProtKB/Swiss-Prot: P35408.1