2型糖尿病患者慢性牙周炎龈下菌群分析

临 口腔医学杂志2004年8月第2O卷第8期 J Clin Stommol，A帔，2004，Vo1．2O，No．8 ·基 础 研 究 · 2型糖尿病患者慢性牙周炎龈下菌群分析 · 453 · 曾红燕 ，杨圣辉 ，刘 颖 (1．首都医科大学宣武医院口腔科 北京 100053；首都医科大学北京口腔医院口腔医学研究所) [摘要] 目的：比较2型糖尿病(DM)慢性牙周炎与非糖尿病慢性牙周炎的龈下菌群。为牙周炎的防治提供参 考。方法：厌氧菌培养、砌 检测技术。结果：①糖尿病慢性牙周炎与非糖尿病慢性牙周炎患者临床指标无明显差 别(P>0．05)。②糖尿病慢性牙周炎的龈下菌群与非糖尿病慢性牙周炎相似，以厌氧菌为主。兼有少量口腔链球 菌；产黑色素类杆菌、核梭杆菌、二氧化碳噬纤维菌、中问普氏菌为牙周优势菌(P<0．01)。③糖尿病慢性牙周炎的 龈下菌群厌氧菌总数、口腔链球菌总数、口腔乳杆菌及核梭杆菌数量少于非糖尿病慢性牙周炎者。结论：2型糖尿 病慢性牙周炎与非糖尿病慢性牙周炎龈下茵群相似，致病菌数量低于非糖尿病牙周炎患者。 [关键词] 糖尿病；慢性牙周炎；菌群 【中图分类号】 R781．4 【文献标识码】 A 【文章编号】 1003—1634(2004)08—0453—03 Su~ n#va flora analysis ot chronic periodontitis patients with type一2 DM ZENG Hong一3un．YANG Sheng — hui。LJU ．Xuanwu Hospital。Ca~tat University ofMedicine。Beijing 100053，China [Abstract]O~ective：To provide referenceforprevention andtr~tingperictiontitisbyaxnparingthe subgingivalflora of type一2 DM patients of chronic perictiontitis with non—DM lxa'kxtontitis．Method：Samples were taken from 64 dis— eased—teeth of 64 patients。21health—teeth of 21 normal people．Patients were taken from chronic periodon titis patients with type一2 DM and chronic periodontits patients with non—DM．A i~lated cultivation of subgingival plaque samples WSS performed by a anaerobe non—sel~tedmedia andother selectivemedia．TheP．intermedia(P．i)ofthe black colony in the non—selective media WaS det~ted by PCR．Result：When the sex。age。clinical marker including PLI。GI。BOP。 PD，AL were not significantly different，the constituents of subgingival flora of the type一2 DM patients with chronic pe— riodontitis were similar to those of the non—DM chronic periodontits patients；the superiority germ of type一2 DM pa— tientsWSSthe anaerobe。speciallyblackgerms。F．n。P．i。andCapnocytophaga(P<0．01)；the arr鲫 toftotal anaeml~。 total Streptococcus spp．Lactobadllus，and F．n W'd8fewer in chronic periodontitis with type一2 DM patienm(P材料

关于××同志的政审材料调查表环保先进个人材料国家普通话测试材料农民专业合作社注销四查四问剖析材料